Skeletal Dysplasia Market: Global Industry Analysis and Forecast (2023-2029)

Skeletal Dysplasia Market size was valued at US$ 2.75 Bn. in 2022. Skeletal Dysplasia will encourage a great deal of transformation in the Medical and Pharmaceutical industries.
Skeletal Dysplasia Market Overview:
Skeletal dysplasias, also known as osteochondrodysplasias, are a diverse collection of heritable illnesses characterized by improper cartilage and bone formation, which results in abnormal skeleton shape and size, as well as the disproportion of the long bones, spine, and skull. Skeletal dysplasia is a hereditary disorder. It's caused by a genetic mutation, which is a malfunction in a certain gene. Each skeletal abnormality is quite uncommon.

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Skeletal Dysplasia Market Dynamics:
Skeletal dysplasias are prevalent cartilage and bone abnormalities that cause a disproportioned low height. The severity of these illnesses can vary greatly, ranging from precocious arthropathy in people of ordinary size to severe dwarfism with neonatal mortality. Skeletal dysplasia is characterized by massive head deformities, delayed growth, bent bones, short upper arms or thighs, arthritis or joint pain, and other symptoms.

Primary diagnosis aids in raising awareness of the illness, which is particularly prevalent in children. Defective genes, which are either inherited from parents or mutated during the development of the fetus, cause this disorder. It's quite tough to spot a faulty gene. As a result, businesses are investing heavily in the research and development of treatments for this rare disease.

The skeletal dysplasia market is being driven by an increase in awareness and early identification of skeletal dysplasia. Aside from technological advancements, the industry is expected to be pushed by another aspect. The major players are investing in the development of a treatment for this illness. Moreover, the incidence of skeletal dysplasia in youngsters is rising. The market is expected to grow as a result of these factors. Gene therapy, which includes allele silencing and cell-based therapy, is one of the more advantageous therapeutic methods. Factors such as the rising frequency of birth abnormalities and inherited illnesses are expected to drive market growth.

The skeletal dysplasia market is driven by increased awareness and early identification of skeletal dysplasia. The development of a therapy for this illness is being funded by major players. Skeletal dysplasia is also becoming more common in children. However, the business is hampered by a lack of awareness regarding skeletal dysplasia and poor diagnosis, particularly in underdeveloped countries.

Skeletal dysplasia is a term that refers to a group of 400 diseases that impact bone formation, including cartilage growth and neurological function. Achondroplasia is the most common of these diseases, affecting about 2.4 out of every 10,000 infants.

The availability of pipeline medications and the commercialization of innovative drugs are driving market growth. Amgen Inc. is working on Denosumab, a phase III clinical trial medication for Osteogenesis Imperfecta (OI). OI is a kind of skeletal dysplasia that causes exceedingly short limbs. It is also known as brittle bone disease. Merck KGaA is also working on a hypochondroplasia treatment with recombinant human growth hormone (r-hGH), which is now in phase II clinical trials. BioMarin is also working on BMN 111, a therapy for achondroplasia in children that is currently in phase III clinical trials. Achondroplasia is a skeletal abnormality that stops cartilage from transforming into bone.
Skeletal Dysplasia Market Segmentation:
By Type, because of the rising prevalence of the disease, HPP dominated the market with 37.4% in 2022. The prevalence of HPP in Europe is predicted to be 1 in every 300,000 births. This factor is driving the growth of the segment.

Through the forecast period, FOP is expected to grow at a CAGR of 13 %. The availability of pipeline drugs and rising disease awareness are some of the reasons driving segment growth through the forecast period. The International Fibrodysplasia Ossificans Progressive Association (IFOPA), for example, is a nonprofit organization that teaches patients and their families about the disease and how to treat it. IFOPA also funds numerous research projects to promote awareness of the condition and find a cure.

By Treatment, Surgery dominated the market with a 46% share in 2022. As it is the most effective treatment option for achondroplasia and HPP. One of the primary aspects driving category expansion is patients' growing choice for procedures. Due to increased activities focusing on developing novel medications for the treatment of certain kinds of skeletal dysplasia such as FOP and MO, the medication segment is expected to grow at the quickest rate through the forecast period.
Skeletal Dysplasia Market Regional Insights:
In 2022, Europe dominated the market for skeletal dysplasia, accounting for 47% of the market. The region's dominance is due to the high adoption of operations for treatment and a growing awareness of the condition. The European Skeletal Dysplasia Network (ESDD), is a non-profit organization that offers a comprehensive diagnostic and research network for skeletal dysplasia. Organizations that undertake various epidemiology studies aid in raising awareness of skeletal dysplasia and educating patients and their families about the disease's prevalence and consequences. These factors are driving the growth of the market in this region.

Because of the increased prevalence of the condition and rising R&D initiatives for the development of effective medications, North America is expected to be the fastest-growing area through the forecast period. XLH affects about 12,000 adults and 3,000 children in the United States. Technological improvements, an increase in medical tourism, and collaborations with national and international organizations in the sector, on the other hand, will prove profitable for this regional industry.

The objective of the report is to present a comprehensive analysis of the Skeletal Dysplasia market to the stakeholders in the industry. The past and current status of the industry with the forecasted market size and trends are presented in the report with the analysis of complicated data in simple language. The report covers all the aspects of the industry with a dedicated study of key players that include market leaders, followers, and new entrants.

PORTER, PESTEL analysis with the potential impact of micro-economic factors of the market have been presented in the report. External as well as internal factors that are supposed to affect the business positively or negatively have been analyzed, which will give a clear futuristic view of the industry to the decision-makers.

The report also helps in understanding the Skeletal Dysplasia market dynamics, structure by analyzing the market segments and projecting the Skeletal Dysplasia market size. Clear representation of competitive analysis of key players by product, price, financial position, product portfolio, growth strategies, and regional presence in the Skeletal Dysplasia market make the report investor’s guide.
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Skeletal Dysplasia Market


Report Coverage
Details


Base Year:
2022
Forecast Period:
2023-2029


Historical Data:
2018 to 2022
Market Size in 2022:
US $ 2.75 Bn.


Forecast Period 2023 to 2029 CAGR:
4.3%
Market Size in 2029:
US $ 3.69 Bn.


 Segments Covered:
by Type
X-linked hypophosphatemia
Hypophosphatasia
Achondroplasia
Fibrodysplasia ossificans progressive
Multiple osteochondromas
Others


by Treatment
Medication
Surgery
Others



Skeletal Dysplasia Market, by Region
North America (United States, Canada and Mexico)
Europe (UK, France, Germany, Italy, Spain, Sweden, Austria and Rest of Europe)
Asia Pacific (China, South Korea, Japan, India, Australia, Indonesia, Malaysia, Vietnam, Taiwan, Bangladesh, Pakistan and Rest of APAC)
Middle East and Africa (South Africa, GCC, Egypt, Nigeria and Rest of ME&A)
South America (Brazil, Argentina Rest of South America)
Skeletal Dysplasia Market Key Players
1. Pfizer
2. Roche
3. AbbVie
4. Merck
5. Novartis
6. Takeda Pharmaceutical
7. Johnson & Johnson
8. Eli Lilly
9. Sanofi
10. Boehringer Ingelheim
11. Daiichi Sankyo
12. Amgen
13. AstraZeneca
14. Astellas
15. BioMarin
16. Regeneron
17. Alexion Pharmaceuticals, Inc.
18. Clementia
19. Ultragenyx Pharmaceutical
20. Alexion Pharmaceuticals

FAQ' s

1] What segments are covered in the Skeletal Dysplasia Market report?
Ans. The segments covered in the Skeletal Dysplasia Market report are based on Type and Treatment.

2] Which region is expected to hold the highest share in the Skeletal Dysplasia Market?
Ans. Europe Region is expected to hold the highest share in the Skeletal Dysplasia Market.

3] What is the market size of the Skeletal Dysplasia Market by 2029?
Ans. The market size of the Skeletal Dysplasia Market by 2029 is US $ 3.69 Bn.

4] What is the forecast period for the Skeletal Dysplasia Market?
Ans. The Forecast period for the Skeletal Dysplasia Market is 2023-2029.

5] What was the market size of the Skeletal Dysplasia Market in 2022?
Ans. The market size of the Skeletal Dysplasia Market in 2022 was US $2.75 Bn.