Hollow Fiber Filtration Market was valued at US$ 267.65 Mn. in 2021 and is estimated to reach a value of US$ 600 Mn. in 2029. Hollow Fiber Filtration Market size is estimated to grow at a CAGR of 14.7% over the forecast period.Hollow Fiber Filtration Market Overview:
Hollow Fiber Filtration (HFFs) is a class of artificial membranes containing a semi-permeable barrier in the form of a hollow fiber. Developed for reverse osmosis applications, hollow fiber filtration has since become prevalent in water treatment, desalination, cell culture, medicine, and tissue engineering. Most commercial hollow fiber membranes are packed into cartridges which can be used for a variety of liquid and gaseous separations. HFFs are commonly produced using artificial polymers. The specific production methods involved are heavily dependent on the type of polymer used as well as its molecular weight. HFM production is commonly referred to as "spinning". Hollow Fiber Filtration includes thousands of long, porous filaments which range from 1-3.5 mm wide. They are situated in a place inside PVC Shell. Hollow fiber has used in all types of filtration which includes microfiltration and reverses osmosis.To know about the Research Methodology:-Request Free Sample Report The report explores the Hollow Fiber Filtration Market's segments (Material, Technique, Application, End-User, and Region). Data has been provided by market participants, and regions (North America, Asia Pacific, Europe, Middle East & Africa, and South America). This market report provides a thorough analysis of the rapid advances that are currently taking place across all industry sectors. Facts and figures, illustrations, and presentations are used to provide key data analysis for the historical period from 2017 to 2020. The report investigates the Hollow Fiber Filtration Market's rivers, limitations, prospects, and barriers. This MMR report includes investor recommendations based on a thorough examination of the Hollow Fiber Filtration Market's contemporary competitive scenario.
Hollow Fiber Filtration Market Dynamics:
Rising Preference for Continuous Manufacturing Influences - Growing investments by biopharmaceutical companies to develop biologics and biosimilars are further expected to increase the number of approved products worldwide and increase the manufacturing of biopharmaceutical drugs. Although small-molecule drugs dominate the global pharmaceuticals market, the share of biologics, biosimilars, and large-molecule drugs is growing due to the launch of new biologics-based drugs and increased revenues from existing biologics. In the bioprocessing industry, filtration is an essential step as a standard unit operation or with other unit operations for separation, isolation, and purification of the biotherapeutics. It is also extremely important for recombinant proteins, vaccines, gene therapy, or cell therapy products. To cater to the rising demand for biopharmaceuticals, companies are focusing on implementing advanced bioprocessing systems throughout the process, including filtration systems such as perfusion systems that utilize hollow fiber filters. The demand for these systems is increasing among biopharmaceutical companies as these systems help decrease the costs associated with complicated steps, increase productivity, and help in adherence to GMP and FDA guidelines for filtration. Increasing Use of Advanced Technologies Propels - The demand for these systems is increasing among biopharmaceutical companies as these systems help decrease the costs associated with complicated steps, increase productivity, and help in adherence to GMP and FDA guidelines for filtration. Hollow fiber nanofiltration (NF) membranes are the latest technology that has gained increased attention in recent years, partly driven by the availability of alternatives to polyamide-based dense separation layers. Moreover, the global market for NF has been growing steadily in recent years and is expected to grow even faster. Compared to the traditional spiral-wound configuration, the hollow fiber geometry provides advantages such as low fouling tendencies and effective hydraulic cleaning possibilities. The alternatives to polyamide layers are typically chemically more stable and thus allow operation and cleaning under more extreme conditions. Therefore, these new NF membranes are of interest for use in a variety of applications. In this review, we provide an overview of the applications and emerging opportunities for these membranes. Next to municipal wastewater and drinking water processes, we have put special focus on industrial applications where hollow fiber NF membranes are employed under more strenuous conditions or used to recover specific resources or solutes. Rise in the Biopharmaceutical Industry - The hollow fiber filtration market is expected to grow due to the increasing use of hollow fiber filtration by pharmaceutical and biotechnology companies. Many companies are investing heavily in the development of biologics and biosimilars. More than half of the drug candidates in the discovery stage are biologics, such as proteins, peptides, and monoclonal antibodies. Biologics are expected to contribute around half of the revenue generated by the top 100 pharmaceutical products in the coming years. Fiber bioreactors employed in the medical and pharmaceutical industries are made of cellulose and synthetic polymers, and they frequently increase permeability, hemocompatibility, and cytocompatibility, all of which are important for hemo purification and liver-assist bioreactors. Hollow fiber filters are increasingly being used in the medical and pharmaceutical industries, as well as in industrial separation applications and medication efficacy testing for cancer therapies. Emerging Economies and Increased Investment Cell-based Research Provides the Opportunities to Market- Various Countries like the US, India, China, and Europe are investing their huge revenue in this market to improve their cell-based biologics to provide growth opportunities for the hollow fiber filtration market players. China is estimated to be a high-growth market for bioprocessing products due to the country's growing government support and private investments. Companies in US and India are also increasingly making biologics-related investments and hiring a skilled workforce for their operations. Also, Research Development investments in markets such as India and Brazil have increased significantly over the past few years. Major Key players are facilitating new projects, R&D centers, and innovation centers in these emerging countries to capitalize on the growth opportunities. For instance, in April 2020, Indian Biologics raised another USD 25 million to help build and kit out a second plant in Gujarat. The new plant will join Chime's first facility, built around a modular manufacturing system from Cytiva Life Sciences. Similarly, in January 2021, Lonza (Switzerland) opened its first manufacturing site for biologics. Lonza will combine Cytiva's KUBio modular facility and single-use equipment with supporting its Good Manufacturing Practice (GMP) manufacturing integrated with its platforms and expertise in development, including cell line construction and process development. Hollow Fiber Filtration Market Trends: Rise in Prevalence of Various Infectious Diseases and Cancer Treatment with Less Cost are Trending Factors for the Market- The increasing various infectious diseases and improvement in biomanufacturing costs have led to renewed interest in the development of single-use technologies that can be readily adapted to continuous processing and provide treatment for diseases like cancer, normal Flu's. The objective of many key players is to use commercially available hollow fiber membranes, originally designed for high-flux hemodialysis, for single-pass tangential flow filtration with high conversions. Experiments were performed with solutions of Immunoglobulin G (IgG) using polysulfone hollow fiber membrane cartridges. The hollow fiber modules were able to provide more than a 10-fold concentration of IgG in a single-pass with exit concentrations greater than 200 g/L. A single dialyzer was able to process 1.4 kg of IgG per day with a total cost of less than $0.004 per g of IgG. Flux-pressure profiles were in good qualitative agreement with a simple model accounting for concentration polarization effects and the variation of flux and pressure with the axial position in the module. These results demonstrate the potential of using these low-cost single-use hollow fiber modules for single-pass tangential flow filtration in continuous biomanufacturing.Hollow Fiber Filtration Market Segment Analysis:
Based on Materials, the Hollow Fiber Filtration Market is segmented into Polymeric, PS/PES, Polyvinylidene Fluoride (PVDF), Other Polymeric Materials, and Ceramic.Polymeric is the segment that holds the largest market share in 2022 and provides a market growth of 15% over the forecasted period. The factors owing to the growth of the segment are because it protects from the Energy, water, affordable healthcare, and global warming which are considered the four major global concerns resulting from resource depletion, record-high oil prices, clean water shortages, high costs of pharmaceuticals, and changing climate conditions. Among many potential solutions, advances in polymeric filtration technology afford direct, effective, and feasible approaches to solving these sophisticated issues. Polymeric Membrane technology encompasses numerous technology areas including materials science and engineering, chemistry and chemical engineering, separation and purification phenomena, molecular simulation, as well as process and product design. Currently, polymeric hollow fiber membranes made using a non-solvent-induced phase inversion process are the dominant products because polymers offer a broad spectrum of materials chemistry and result in membranes with desirable physicochemical properties for diverse applications. Their low cost and ease of fabrication make polymeric membranes superior to inorganic membranes. Based on Application, the Hollow Fiber Filtration Market is segmented into Continuous Cell Perfusion, Harvest and Clarification, and Concentration & Diafiltration.
Continuous Cell Perfusion holds the largest market share of hollow fiber filtration because of the factors which owing to make a CAGR of 6.5% over the forecasted period, the growth factors are perfusion permits culture homogeneity rather than a feed-and-fast regime, and has permitted the development of bioreactors which have no gas headspace and significant scale-up of cell density. A wide range of culture systems has been reviewed with the emphasis on attached cells. The prime objective of using perfusion techniques is to achieve a controlled and homogeneous environment within the bioreactor. The use of perfusion to keep small fragments of tissue viable in microscope chambers developed in complexity, culminating in Rose's dual-rotary circumfusion system. The cogenerator also encouraged the development of perfusion systems for substrate or anchorage-dependent cells. The use of perfusion techniques reduces the risk of continuous entry and exit of materials from the reactor, often through vulnerable tubing in pumps, etc. Both the bioreactor and the associated equipment should be easily evaluated and handled with this in mind by manufacturers to make their products increase the consumption of perfusion cells in hollow fiber filtration. Based on Technique, the Hollow Fiber Filtration Market is segmented into Microfiltration and Ultrafiltration.
Micro-Filtration covers the highest market size and provides the largest market growth of 14% over the forecasted period, the various properties are considered as the factors for the growth of this segment, and its facilities other properties like availability of a wide range of pore sizes which have vast applications such as separation of a virus, bacteria, aerosols, and innumerable macromolecules from fluids, without the requirement of autoclaving a procedure. Microfiltration is a widely used membrane process for various applications, such as wastewater treatment, juice clarification, protein separation, and bacteria separation. The microfiltration works on the sieving principle with pore sizes in the range of 0.1–10 μm. Both polymeric, as well as ceramic membranes, are used in the microfiltration membrane process-based applications of various industries. Polymeric membranes due to their low cost and high packing densities are more widely used than ceramic membranes. However, the disadvantages associated with polymeric membranes, such as fouling and short lifespan make them unfavorable for industrial applications. On the other hand, ceramic membranes are tough with longer lifespans and low fouling tendencies. Also, because of their stability against harsh conditions allow the use of different cleaning technologies to reduce fouling. Therefore, ceramic membranes make the best option for industrial-scale applications. Based on End-User, the Hollow Fiber Filtration Market is segmented into Pharmaceuticals & Biotechnology Manufacturers, Contract Research & Manufacturing organizations, Research & Development Departments, and Others. Pharmaceuticals & Biotechnology Manufacturers are the most dominating segment and hold the largest market share of greater than 30% in 2022 and with the highest CAGR of 7.4% over the forecasted period. The factor owing to the growth of the segment is the increase in the pharmaceutical industry has long been one of the most innovative industries and, unlike industries such as computers and aircraft, has remained relatively unconcentrated. In recent years, however, there have been contrasting industry developments that could have far-reaching, long-run effects on the industry's structure. The impact of the entry of new biotechnology firms, the increasing real cost of innovation, and the recent important mergers among leading firms. Also, regression analysis reveals disproportionately high innovative contributions from both new biotechnology firms and the very largest multinational pharmaceutical firms.
Hollow Fiber Filtration Market Regional Insights:
The North American Hollow Fiber Filtration Market region is expected to witness significant growth at a CAGR of 9.6% through the forecast period. North America dominates the hollow fiber filtration market due to the increasing adoption of advanced manufacturing techniques and the presence of major players in the region and also in terms of the highest growth rate in terms of revenue in the forecast period of 2022-2029. The regions also have a high share of the market is scribed to the fact that regional firms are focusing primarily on developing innovative products such as perfusion systems. In addition, the growing demand for filtering systems in the biopharmaceuticals industry along with the cost-efficiency and comfort of dealing with hollow fiber filters is further likely to drive the regional market. The Asia Pacific market is also projected to witness the highest growth rate during the forecast period, primarily because of the innovation, a giant talent pool of scientists, low labor, and manufacturing costs. The region has also witnessed mass production because of technology and a rise in continuous manufacturing instead of batch production in the past years. This region is considered a lucrative market for foreign investors, with key market players having their presence in the region. Over the past years, CMOs in the Asia Pacific region have impacted the global pharmaceutical manufacturing market. Several small and medium-scale CMOS set up in APAC have obtained US FDA approval for their operations and completed GMP certifications, thus driving the region's hollow fiber filtration market. The objective of the report is to present a comprehensive analysis of the global Hollow Fiber Filtration Market to the stakeholders in the industry. The past and current status of the industry with the forecasted market size and trends are presented in the report with the analysis of complicated data in simple language. The report covers all the aspects of the industry with a dedicated study of key players that include market leaders, followers, and new entrants. PORTER, PESTEL analysis with the potential impact of micro-economic factors of the market have been presented in the report. External as well as internal factors that are supposed to affect the business positively or negatively have been analyzed, which will give a clear futuristic view of the industry to the decision-makers. The reports also help in understanding the Hollow Fiber Filtration Market dynamic and structure by analyzing the market segments and projecting the Hollow Fiber Filtration Market size. Clear representation of competitive analysis of key players by Design, price, financial position, product portfolio, growth strategies, and regional presence in the Hollow Fiber Filtration Market make the report investor’s guide.Hollow Fiber Filtration Market Scope: Inquire before buying
Global Hollow Fiber Filtration Market Report Coverage Details Base Year: 2021 Forecast Period: 2022-2029 Historical Data: 2017 to 2021 Market Size in 2021: US$ 267.65 Mn. Forecast Period 2022 to 2029 CAGR: 14.7% Market Size in 2029: US$ 600 Mn. Segments Covered: by Materials • Polymeric • PS/PES • Polyvinylidene Fluoride (PSDF) • Other Polymeric Materials • Ceramic by Application • Continuous Cell Perfusion • Harvest and Clarification • Concentration & Diafiltration by Technique • Microfiltration • Ultrafiltration by End-User • Pharmaceuticals & Biotechnology Manufacturers • Contract Research & Manufacturing Organization • Research & Development Departments • Others Hollow Fiber Filtration Market by Region
• North America • Europe • Asia Pacific • The Middle East and Africa • SouthAmericaHollow Fiber Filtration Market Key Players:
• GE Healthcare • Danaher Corporation • Asahi Kasei Corporation • Repligen Corporation • Parker-Hannifin Corporation • Koch Membrane Systems • MMS Membrane • Watersep Bioseparation Corporation • Cantel Medical Corporation • Kuraray Co., Ltd. • Koch Industries Inc., • Alpha Plan GmbH • Antylia Scientific Frequently Asked Questions: 1] What are the leading market players active in Hollow Fiber Filtration Market? Ans. The leading market players active in Hollow Fiber Filtration Market are GE Healthcare and Parker-Hannifin Corporation. 2] What is the market in the Hollow Fiber Filtration Market in 2022? Ans. The market size in the Hollow Fiber Filtration Market in 2021 is US$ 267.65 Million. 3] What is the market in the Hollow Fiber Filtration Market in 2029? Ans. The market size in the Hollow Fiber Filtration Market in 2029 is US$ 600 Million. 4] What is the projections period for the future that would help in taking further strategic steps? Ans. The Projections period for the future strategy for Hollow Fiber Filtration Market is 2022-2029. 5] What Segments and regions will drive the market growth? Ans. The Segments and regions that drive the market growth are Material, Application, Technique, and End-User, and the region is North America.