The Orthopedic Biomaterial Market size was valued at USD 15.9 Bn in 2022 and is expected to reach USD 38.4 Bn by 2029, at a CAGR of 10.6 % from forecast 2023 to 2029Orthopedic Biomaterial Market Overview
Orthopedic biomaterials started from temporary implants to fix bone to permanent implant materials and bio-absorbable implants. In the future, orthopedic biomaterial will find a place in the regeneration of living tissue, as well as replacing it. The orthopedic biomaterial market is a rapidly growing sector within the healthcare industry, driven by the increasing prevalence of musculoskeletal disorders, the rising geriatric population, and advancements in biomaterial technology. Orthopedic biomaterials are synthetic or natural materials that are used to repair or replace damaged bones, joints, ligaments, and tendons, promoting tissue regeneration and healing. The overview of the Orthopedic Biomaterial Market adds to the market’s objectives. It includes leading competitors and their market value with their current trending skims, strategies, targets, and products. The report put light on the market’s recent growth as well as its informative past. The Orthopedic Biomaterial Market overview presents a brief synopsis of a commercial or industrial market. The aim was to provide a current snapshot of a market in order to better understand its key features. To know about the Research Methodology :- Request Free Sample ReportOrthopedic Biomaterial Market Scope and Research Methodology
The scope of the research on the orthopedic biomaterial market encompasses the analysis of the global market, including major regions such as North America, Europe, Asia-Pacific, and the Rest of the World. The study focuses on the various types of orthopedic biomaterials used in applications such as joint replacements, fracture fixation, spine surgeries, and tissue engineering. The Orthopedic Biomaterial market analysis includes both synthetic and natural biomaterials used in orthopedics. Furthermore, the research covers the competitive landscape, key market players, market trends, drivers, challenges, and opportunities influencing the orthopedic biomaterial market. The research begins with extensive data collection from various sources, including industry reports, market studies, academic journals, company websites, and government databases. Primary research through interviews with industry experts, orthopedic surgeons, and key opinion leaders may also be conducted to gather insights and validate the information. The research includes a detailed analysis of key market players, their product portfolios, business strategies, and recent developments. This analysis helps in understanding the competitive landscape and market positioning of various companies in the orthopedic biomaterial market.Orthopedic Biomaterial Market Dynamics
Increasing Adoption of Bioactive Materials: Bioactive materials, such as bioactive glass and ceramics, are gaining traction in the orthopedic biomaterial market. These materials have the ability to bond with living tissues, promoting cellular attachment and facilitating bone regeneration. The increasing adoption of bioactive materials in orthopedic implants and bone grafts is driven by their biocompatibility, osteoconductive properties, and ability to stimulate tissue growth, leading to improved patient outcomes. Growing Demand for Personalized Medicine: There is a rising demand for personalized medicine in orthopedics, driven by the need for customized solutions that cater to the unique needs of individual patients. Biomaterials play a crucial role in personalized medicine, as they are tailored to specific patient requirements, such as biodegradability, mechanical strength, and surface properties. This demand for patient-specific orthopedic biomaterials is driving research and development efforts in the field and fueling the orthopedic biomaterial market growth. Expansion of 3D Printing Technology: 3D printing technology has revolutionized the orthopedic biomaterial market by enabling the production of patient-specific implants and scaffolds with precise dimensions and complex geometries. This technology allows for the fabrication of implants that closely mimic natural bone structures, enhancing osseointegration and reducing the risk of implant failure. The expanding applications of 3D printing in orthopedics, coupled with advancements in biomaterials suitable for 3D printing, are driving orthopedic biomaterial market growth. Rising Focus on Regenerative Medicine: Regenerative medicine, which aims to restore or replace damaged tissues and organs, is gaining prominence in orthopedics. Biomaterials serve as a crucial component in regenerative medicine approaches, providing scaffolds or matrices for tissue regeneration. The growing focus on regenerative medicine for the treatment of musculoskeletal disorders, including tissue engineering, stem cell therapies, and gene therapy, is driving the demand for orthopedic biomaterial market. Technological Advancements in Surface Modification: Surface modification techniques, such as coating technologies and nanostructuring, are advancing the functionality and performance of orthopedic biomaterials. These techniques enhance the biocompatibility, wear resistance, antibacterial properties, and drug delivery capabilities of biomaterials. The continuous advancements in surface modification technologies are expanding the applications of orthopedic biomaterials and driving the orthopedic biomaterial market growth. Growing Awareness of Biodegradable Biomaterials: Biodegradable biomaterials are gaining prominence in the orthopedic sector due to their ability to degrade over time, eliminating the need for implant removal surgeries. These biomaterials offer advantages such as reduced risk of infection, improved healing, and avoidance of long-term complications associated with permanent implants. The growing awareness of the benefits of biodegradable biomaterials among healthcare professionals and patients is fueling their adoption and driving orthopedic biomaterial market growth. Increasing Sports Injuries and Trauma Cases: Sports injuries and trauma cases, such as fractures, ligament tears, and cartilage damage, are on the rise globally. The demand for orthopedic biomaterials used in the treatment of sports injuries and trauma cases is increasing, driven by the need for effective and durable solutions that restore function and mobility. Biomaterials, such as bone grafts, implants, and tissue scaffolds, play a vital role in the repair and regeneration of injured tissues, supporting orthopedic biomaterial market growth. High Cost of Biomaterials: The cost of orthopedic biomaterials is significantly high, which poses a challenge to widespread adoption, particularly in emerging economies. The high cost of biomaterials can limit their accessibility, especially in resource-constrained healthcare systems, and may hinder orthopedic biomaterial market growth. Stringent Regulatory Approval Process: The orthopedic biomaterial market is subject to stringent regulatory requirements, including pre-market approvals and extensive clinical trials. These regulatory processes are time-consuming and costly, delaying the introduction of new biomaterial products to the market and adding to the overall development costs. Increasing Emphasis on Minimally Invasive Procedures: The growing preference for minimally invasive surgical procedures in orthopedics presents opportunities for biomaterials that support these techniques. Biomaterials used in minimally invasive implants, tissue scaffolds, and regenerative therapies can enhance patient outcomes, reduce hospital stays, and minimize scarring. Capitalizing on the demand for minimally invasive procedures can open avenues for orthopedic biomaterial market expansion.Orthopedic Biomaterial Market Segment Analysis
Bioactive Materials: Bioactive materials, such as bioactive glass, ceramics, and hydroxyapatite, have the ability to bond with living tissues, promoting cellular attachment and facilitating bone regeneration. These materials are used in orthopedic implants, bone grafts, and tissue engineering applications, providing enhanced osseointegration and improved patient outcomes. Biodegradable Polymers: Biodegradable polymers are designed to degrade over time and are widely used in orthopedic applications. These polymers provide temporary support or scaffolding for tissue regeneration, gradually breaking down as the tissue heals. Biodegradable polymers find applications in fracture fixation devices, drug delivery systems, and tissue engineering scaffolds. Metals and Alloys: Metals and alloys have been traditionally used in orthopedic implants due to their strength and durability. Materials such as stainless steel, titanium, and cobalt-chromium alloys are used in joint replacements, fracture fixation devices, and spinal implants. These materials provide mechanical stability and long-term performance in orthopedic applications. Polymeric Hydrogels: Polymeric hydrogels are three-dimensional networks of hydrophilic polymers that absorb and retain large amounts of water. These materials offer high water content, soft tissue-like properties, and excellent biocompatibility, making them suitable for applications such as cartilage repair, tissue engineering, and drug delivery systems. Composite Materials: Composite biomaterials are formed by combining two or more different materials to create synergistic properties. For example, composite materials consist of a combination of polymers and ceramics, providing the benefits of both materials. Composite biomaterials are used in various orthopedic applications, including bone graft substitutes, implant coatings, and tissue engineering scaffolds. Natural Biomaterials: Natural biomaterials derived from biological sources, such as collagen, hyaluronic acid, and chitosan, have gained attention in the orthopedic biomaterial market. These materials offer biocompatibility, bioactivity, and mimicry of natural extracellular matrix, promoting tissue regeneration and healing. Natural biomaterials find applications in cartilage repair, wound healing, and tissue engineering. Competitive Analysis of the Orthopedic Biomaterial Market Zimmer Biomet Holdings Inc.: In 2021, Zimmer Biomet announced the launch of the Persona IQ, a personalized knee system that combines artificial intelligence, robotics, and intraoperative data collection to optimize patient outcomes. In 2020, Zimmer Biomet acquired A&E Medical Corporation, a leading manufacturer of cardiovascular medical devices, to expand its product portfolio. Some of Zimmer Biomet's flagship orthopedic biomaterial products include the Trabecular Metal Technology for joint replacements, Grafton DBM (Demineralized Bone Matrix) for bone grafting, and the Signature Personalized Patient Care System for knee replacements. Stryker Corporation introduced the Tritanium TL Curved Posterior Lumbar Cage in 2021, a 3D-printed interbody fusion cage designed for use in lumbar spine surgery. In 2020, Stryker collaborated with Hospital for Special Surgery to develop additive manufacturing technologies and patient-specific devices for orthopedic applications. Stryker's notable orthopedic biomaterial products include the Triathlon Total Knee System, Mako Robotic-Arm Assisted Surgery System, and the BioCrux PCL (Posterior Cruciate Ligament) for knee reconstruction. Johnson & Johnson (DePuy Synthes) launched the ATTUNE Cementless Knee System in 2021, providing a cementless option for knee replacements. In 2020, Johnson & Johnson acquired the 3D printing technology company TissueGen, Inc., to strengthen its capabilities in the field of regenerative medicine and biomaterials. DePuy Synthes offers orthopedic biomaterial products such as the Attune Knee System, TruMatch Personalized Solutions, and the CORAIL Hip System. Medtronic launched the Grafton plus DBM (Demineralized Bone Matrix) in 2021, providing a comprehensive bone grafting solution for orthopedic procedures. In 2020, Medtronic collaborated with Titan Spine to enhance its spine portfolio with surface-enhanced titanium implants for spinal fusion procedures. Medtronic's flagship orthopedic biomaterial products include the Infuse Bone Graft for spine surgeries, Restorative Biologics for bone repair, and the Tapered Screw-Vent Implant for dental applications. Baxter introduced the Novabone Putty in 2021, a moldable, bioactive bone graft substitute for orthopedic applications. In 2020, Baxter acquired Seprafilm Adhesion Barrier from Sanofi, expanding its surgical portfolio with a bioresorbable adhesion barrier. Baxter's orthopedic biomaterial offerings include the Actifuse Synthetic Bone Graft for bone fusion and the Artists Fibrin Sealant for tissue adhesion and sealing.Regional Analysis of the Orthopedic Biomaterial Market
North America: Largest Market Holder: North American Orthopedic Biomaterial Market is one of the largest markets, with the United States being the dominant player in the region. The presence of established healthcare infrastructure, high healthcare expenditure, and a strong focus on technological advancements contribute to its market leadership. Factors such as a large aging population, increasing prevalence of musculoskeletal disorders, and rising demand for advanced orthopedic treatments drive market growth in North America. Additionally, favorable reimbursement policies and a supportive regulatory environment further propel the market. Europe: 2nd Largest Market: Europe is a significant market for orthopedic biomaterials, with countries like Germany, the United Kingdom, and France leading the region. The presence of well-developed healthcare systems, high awareness regarding orthopedic advancements, and strong investments in research and development contribute to its market position. The aging population in Europe, coupled with a high incidence of orthopedic conditions, fuels the demand for orthopedic biomaterials. The region also emphasizes the adoption of advanced technologies, such as 3D printing and regenerative medicine, supporting market growth. Asia Pacific: 3rd Largest Market: Asia Pacific is a rapidly growing market for orthopedic biomaterials, with countries like China, Japan, and India driving regional growth. The increasing healthcare infrastructure, rising disposable income, and a large patient pool contribute to the market's expansion. The growing geriatric population, increasing prevalence of orthopedic disorders, and rising demand for advanced healthcare solutions are key drivers in the Asia Pacific region. Additionally, the presence of a large medical tourism industry in countries like India and Thailand further boosts market growth. Latin America: 4th Largest Market: Latin America holds a significant Orthopedic Biomaterial Market share, with countries like Brazil, Mexico, and Argentina playing a vital role. The region's improving healthcare infrastructure, rising healthcare expenditure, and increasing awareness about advanced orthopedic treatments contribute to its market position. The prevalence of orthopedic conditions, sports injuries, and trauma cases in the region drives the demand for orthopedic biomaterials. Additionally, the adoption of minimally invasive procedures and a growing focus on regenerative medicine offer opportunities for market growth in Latin America.Orthopedic Biomaterial Market Scope: Inquire before buying
Orthopedic Biomaterial Market Report Coverage Details Base Year: 2022 Forecast Period: 2023-2029 Historical Data: 2017 to 2022 Market Size in 2022: USD 15.9 Bn Forecast Period 2023 to 2029 CAGR: 10.6% Market Size in 2029: USD 38.4 Bn Segments Covered: by Bioactive Materials Bioactive Glass Ceramics Hydroxyapatite by Biodegradable Polymers Fracture Fixation Devices Drug Delivery Systems Tissue Engineering Scaffolds by Metal and Alloys Stainless Steel Alloys Titanium Alloys Cobalt-Chromium Alloys by Polymeric Hydrogels Cartilage Repair Tissue Engineering Drug Delivery Systems by Composite Materials Bone Graft Substitutes Implant Coatings Tissue Engineering Scaffolds by Natural Biomaterials Cartilage Repair Wound Healing Tissue Engineering Hydraulic Breaker Market, by Region
North America (United States, Canada and Mexico) Europe (UK, France, Germany, Italy, Spain, Sweden, Austria and Rest of Europe) Asia Pacific (China, South Korea, Japan, India, Australia, Indonesia, Malaysia, Vietnam, Taiwan, Bangladesh, Pakistan and Rest of APAC) South America (Brazil, Argentina Rest of South America) Middle East & Africa (South Africa, GCC, Egypt, Nigeria and Rest of ME&A)Hydraulic Breaker Key players
1. Handan Hanbing Machinery Manufacturing Co.,Ltd. 2. Mazio Attachments 3. Epiroc 4. Atlas Copco 5. Komatsu 6. Toku-America Inc. 7. Kinshofer 8. Ace Hammer Co., Ltd. 9. J C Bamford Excavators Ltd 10.Takeuchi 11.Furukawa 12.Konekesko 13.Rammer 14.Stanley Hydraulics 15.John Deere 16.Indeco 17.Everdigm 18.Breaker Category Inc 19.Hammer srl 20.Soosan Heavy Industries 21.Volvo 22.Miller UK 23.Nuosen Machinery 24.NPK 25.Montabert Frequently Asked Questions about Orthopedic Biomaterial Market 1.What are orthopedic biomaterials? Ans: Orthopedic biomaterials are materials specifically designed and engineered for use in orthopedic applications, such as joint replacements, bone grafts, fracture fixation, and tissue engineering. These biomaterials possess biocompatibility, and mechanical strength, and have properties that promote tissue regeneration and integration. 2.What factors are driving the growth of the orthopedic biomaterial market? Ans: The growth of the orthopedic biomaterial market is primarily driven by factors such as the increasing prevalence of orthopedic disorders, a rising aging population, advancements in biomaterial technologies, growing demand for minimally invasive procedures, and the emphasis on regenerative medicine and tissue engineering. 3: What are the main types of orthopedic biomaterials? Ans: The main types of orthopedic biomaterials include metals and alloys (such as titanium and stainless steel), ceramics (such as hydroxyapatite), polymers (both biodegradable and non-biodegradable), composite materials, and natural biomaterials (such as collagen and hyaluronic acid). 4: What are the key challenges in the orthopedic biomaterial market? Ans: Some key challenges in the orthopedic biomaterial market include the high cost of biomaterials, stringent regulatory approval processes, concerns about long-term safety and efficacy, limited clinical evidence supporting certain biomaterials, and the need for continuous technological advancements to meet evolving patient needs. 5: How does the orthopedic biomaterial market vary regionally? Ans: The orthopedic biomaterial market varies regionally based on factors such as healthcare infrastructure, economic development, regulatory frameworks, and population demographics. North America and Europe are leading markets due to established healthcare systems, while the Asia Pacific region is experiencing rapid growth due to rising healthcare investments and an increasing patient population.
1. Orthopedic Biomaterial Market: Research Methodology 2. Orthopedic Biomaterial Market: Executive Summary 3. Orthopedic Biomaterial Market: Competitive Landscape 3.1. MMR Competition Matrix 3.2. Competitive Landscape 3.3. Key Players Benchmarking 3.4. Market Structure 3.4.1. Market Leaders 3.4.2. Market Followers 3.4.3. Emerging Players 3.5. Consolidation of the Market 4. Orthopedic Biomaterial Market: Dynamics 4.1. Market Trends by Region 4.1.1. North America 4.1.2. Europe 4.1.3. Asia Pacific 4.1.4. Middle East and Africa 4.1.5. South America 4.2. Market Drivers by Region 4.2.1. North America 4.2.2. Europe 4.2.3. Asia Pacific 4.2.4. Middle East and Africa 4.2.5. South America 4.3. Market Restraints 4.4. Market Opportunities 4.5. Market Challenges 4.6. PORTER’s Five Forces Analysis 4.7. PESTLE Analysis 4.8. Value Chain Analysis 4.9. Regulatory Landscape by Region 4.9.1. North America 4.9.2. Europe 4.9.3. Asia Pacific 4.9.4. Middle East and Africa 4.9.5. South America 5. Orthopedic Biomaterial Market: Segmentation (by Value USD and Volume Units) 5.1. Orthopedic Biomaterial Market, by Bioactive Materials (2022-2029) 5.1.1. Bioactive Glass 5.1.2. Ceramics 5.1.3. Hydroxyapatite 5.2. Orthopedic Biomaterial Market, by Biodegradable Polymers (2022-2029) 5.2.1. Fracture Fixation Devices 5.2.2. Drug Delivery Systems 5.2.3. Tissue Engineering Scaffolds 5.3. Orthopedic Biomaterial Market, by Metal and Alloys (2022-2029) 5.3.1. Stainless Steel Alloys 5.3.2. Titanium Alloys 5.3.3. Cobalt-Chromium Alloys 5.4. Orthopedic Biomaterial Market, by Polymeric Hydrogels (2022-2029) 5.4.1. Cartilage Repair 5.4.2. Tissue Engineering 5.4.3. Drug Delivery Systems 5.5. Orthopedic Biomaterial Market, by Composite Materials (2022-2029) 5.5.1. Bone Graft Substitutes 5.5.2. Implant Coatings 5.5.3. Tissue Engineering Scaffolds 5.6. Orthopedic Biomaterial Market, by Natural Biomaterials (2022-2029) 5.6.1. Cartilage Repair 5.6.2. Wound Healing 5.6.3. Tissue Engineering 5.7. Orthopedic Biomaterial Market, by Region (2022-2029) 5.7.1. North America 5.7.2. Europe 5.7.3. Asia Pacific 5.7.4. Middle East and Africa 6. North America Orthopedic Biomaterial Market (by Value USD and Volume Units) 6.1. North America Orthopedic Biomaterial Market, by Bioactive Materials (2022-2029) 6.1.1. Bioactive Glass 6.1.2. Ceramics 6.1.3. Hydroxyapatite 6.2. North America Orthopedic Biomaterial Market, by Biodegradable Polymers (2022-2029) 6.2.1. Fracture Fixation Devices 6.2.2. Drug Delivery Systems 6.2.3. Tissue Engineering Scaffolds 6.3. North America Orthopedic Biomaterial Market, by Metal and Alloys (2022-2029) 6.3.1. Stainless Steel Alloys 6.3.2. Titanium Alloys 6.3.3. Cobalt-Chromium Alloys 6.4. North America Orthopedic Biomaterial Market, by Polymeric Hydrogels (2022-2029) 6.4.1. Cartilage Repair 6.4.2. Tissue Engineering 6.4.3. Drug Delivery Systems 6.5. North America Orthopedic Biomaterial Market, by Composite Materials (2022-2029) 6.5.1. Bone Graft Substitutes 6.5.2. Implant Coatings 6.5.3. Tissue Engineering Scaffolds 6.6. North America Orthopedic Biomaterial Market, by Natural Biomaterials (2022-2029) 6.6.1. Cartilage Repair 6.6.2. Wound Healing 6.6.3. Tissue Engineering 6.7. North America Orthopedic Biomaterial Market, by Country (2022-2029) 6.7.1. United States 6.7.2. Canada 6.7.3. Mexico 7. Europe Orthopedic Biomaterial Market (by Value USD and Volume Units) 7.1. Europe Orthopedic Biomaterial Market, by Bioactive Materials (2022-2029) 7.2. Europe Orthopedic Biomaterial Market, by Biodegradable Polymers (2022-2029) 7.3. Europe Orthopedic Biomaterial Market, by Metal and Alloys (2022-2029) 7.4. Europe Orthopedic Biomaterial Market, by Polymeric Hydrogels (2022-2029) 7.5. Europe Orthopedic Biomaterial Market, by Composite Materials (2022-2029) 7.6. Europe Orthopedic Biomaterial Market, by Natural Biomaterials (2022-2029) 7.7. Europe Orthopedic Biomaterial Market, by Country (2022-2029) 7.7.1. UK 7.7.2. France 7.7.3. Germany 7.7.4. Italy 7.7.5. Spain 7.7.6. Sweden 7.7.7. Austria 7.7.8. Rest of Europe 8. Asia Pacific Orthopedic Biomaterial Market (by Value USD and Volume Units) 8.1. Asia Pacific Orthopedic Biomaterial Market, by Bioactive Materials (2022-2029) 8.2. Asia Pacific Orthopedic Biomaterial Market, by Biodegradable Polymers (2022-2029) 8.3. Asia Pacific Orthopedic Biomaterial Market, by Metal and Alloys (2022-2029) 8.4. Asia Pacific Orthopedic Biomaterial Market, by Polymeric Hydrogels (2022-2029) 8.5. Asia Pacific Orthopedic Biomaterial Market, by Composite Materials (2022-2029) 8.6. Asia Pacific Orthopedic Biomaterial Market, by Natural Biomaterials (2022-2029) 8.7. Asia Pacific Orthopedic Biomaterial Market, by Country (2022-2029) 8.7.1. China 8.7.2. S Korea 8.7.3. Japan 8.7.4. India 8.7.5. Australia 8.7.6. Indonesia 8.7.7. Malaysia 8.7.8. Vietnam 8.7.9. Taiwan 8.7.10. Bangladesh 8.7.11. Pakistan 8.7.12. Rest of Asia Pacific 9. Middle East and Africa Orthopedic Biomaterial Market (by Value USD and Volume Units) 9.1. Middle East and Africa Orthopedic Biomaterial Market, by Bioactive Materials (2022-2029) 9.2. Middle East and Africa Orthopedic Biomaterial Market, by Biodegradable Polymers (2022-2029) 9.3. Middle East and Africa Orthopedic Biomaterial Market, by Metal and Alloys (2022-2029) 9.4. Middle East and Africa Orthopedic Biomaterial Market, by Polymeric Hydrogels (2022-2029) 9.5. Middle East and Africa Orthopedic Biomaterial Market, by Composite Materials (2022-2029) 9.6. Middle East and Africa Orthopedic Biomaterial Market, by Natural Biomaterials (2022-2029) 9.7. Middle East and Africa Orthopedic Biomaterial Market, by Country (2022-2029) 9.7.1. South Africa 9.7.2. GCC 9.7.3. Egypt 9.7.4. Nigeria 9.7.5. Rest of ME&A 10. South America Orthopedic Biomaterial Market (by Value USD and Volume Units) 10.1. South America Orthopedic Biomaterial Market, by Bioactive Materials (2022-2029) 10.2. South America Orthopedic Biomaterial Market, by Biodegradable Polymers (2022-2029) 10.3. South America Orthopedic Biomaterial Market, by Metal and Alloys (2022-2029) 10.4. South America Orthopedic Biomaterial Market, by Polymeric Hydrogels (2022-2029) 10.5. South America Orthopedic Biomaterial Market, by Composite Materials (2022-2029) 10.6. South America Orthopedic Biomaterial Market, by Natural Biomaterials (2022-2029) 10.7. South America Orthopedic Biomaterial Market, by Country (2022-2029) 10.7.1. Brazil 10.7.2. Argentina 10.7.3. Rest of South America 11. Company Profile: Key players 11.1. Zimmer Biomet Holdings Inc. 11.1.1. Company Overview 11.1.2. Financial Overview 11.1.3. Business Portfolio 11.1.4. SWOT Analysis 11.1.5. Business Strategy 11.1.6. Recent Developments 11.2. Stryker Corporation 11.3. Johnson & Johnson (DePuy Synthes) 11.4. Medtronic plc 11.5. Baxter International Inc. 11.6. Smith & Nephew plc 11.7. Integra LifeSciences Holdings Corporation 11.8. Wright Medical Group N.V. 11.9. Arthrex, Inc. 11.10. Aesculap, Inc. (B. Braun Melsungen AG) 11.11. CONMED Corporation 11.12. DJO Global Inc. 11.13. Orthofix Medical Inc. 11.14. NuVasive, Inc. 11.15. Globus Medical, Inc. 11.16. Biomatlante 11.17. Evonik Industries AG 11.18. Collagen Matrix, Inc. 11.19. Heraeus Holding GmbH 11.20. DSM Biomedical 12. Key Findings 13. Industry Recommendation