High Throughput Screening Market – Global Market Size, Strategic Growth Drivers, Risk Assessment Framework, Regulatory Landscape Review, Competitive Intensity Mapping & Long-Term Industry Outlook to 2030
Overview
High Throughput Screening Market size was valued at USD 25.5 Billion in 2023 and the total High Throughput Screening Market revenue is expected to grow at a CAGR of 10.8% from 2024 to 2030, reaching nearly USD 52.28 Billion by 2030.
High Throughput Screening Market Product Definition
High-throughput screening (HTS) is a drug discovery process that allows automated testing of large numbers of chemical and/or biological compounds for a specific biological target. High-throughput screening methods are widely used in the pharmaceutical industry, leveraging robotics and automation to rapidly test the biological or biochemical activity of a large number of molecules, like drugs. HTS is a suitable tool for assessing, for example, pharmacological targets, pharmacologically profiling agonists and antagonists for receptors (such as GPCRs) and enzymes. Using robotics, liquid handling devices, data processing/control software, and sensitive detectors, high-throughput screening permits a researcher to rapidly conduct millions of genetic, chemical, or pharmacological tests.
The report study has analyzed revenue impact of covid-19 pandemic on the sales revenue of market leaders, market followers and disrupters in the report and same is reflected in our analysis.
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High Throughput Screening Market Dynamics
The Research Report gives a detailed account of the drivers and restraints in the high throughput screening market. High-throughput screening (HTS) is a process used in drug discovery to identify hits from compound libraries that may become leads for medicinal chemistry optimization. The initiatives are taken by pharmaceutical and biotechnology firms, rising R&D spending, technological developments in HTS, and the obtainability of government funding and undertaking capital investments.
HTS is used in stem cell research for the identification of target hits, examination of functional activity; and the valuation of absorption, metabolism, distribution, and excretion characteristics. The use of human stem cells instead of mouse stem cells offers many opportunities for refining the clinical expectedness of preclinical drug discovery and development, which provides lots of opportunities in this market.
However, HTS includes many steps like target selection and characterization, reagent preparation, assay development, compound screening, and hit validation in secondary assays. According to the complexity of the target and assay, their time and cost get vary. The process of reagent and assay development for primary and secondary makes it more costly. Additionally, HTS instruments, such as flow cytometers and liquid handlers, are too much costly. These factors restraints the growth of the High-throughput screening market.
High Throughput Screening Market Segment Analysis
Based on Technology, the 3D cell segment is expected to grow at a CAGR of xx% during the forecast period. 3D cells show more realistic properties while testing in the natural environment and other cell-associated operations, supported for drug design and discovery. The growth of this segment is compelled mostly by the growing focus on developing replacements to animal testing, rising focus on modified drug, the up surging prevalence of chronic diseases, and the accessibility of funding for research. Normal differentiation and polarization of epithelial cells are vital for the formation of duct-like structures in vitro conditions, which can be achieved when the cells are cultivated in 3D cultures. Furthermore, the synergistic effect necessary for the interactions of cell-cell and cell-extracellular matrix (ECM), which can control the expression of molecules involved in cell differentiation, is accomplished in 3D cell cultures.
Regional Analysis
The North American region has dominated the market with US$ xx Mn. North America is seen to be an important contributor to the market share, mostly owing to the prominence placed on research and development in pharmaceutical companies, the acceptance of drug detection techniques, government support, and funding and the great number of companies producing HTS products and services.
European markets have a large share of the market because of advancements in chemical testing, development of software and hardware that can automate testing, government initiatives for drug testing, R&D by several research centers and the upsurge in the application of data processing software for HTS. Asia Pacific region has experienced a rising popularity of high throughput screening techniques. In 2018, Charles River Laboratories' total revenue was $2.3 billion was high as compared to Bio-Rad Laboratories. Bio-Rad Laboratories' annual revenue for 2018 was $2.289B.
High Throughput Screening Market Key Agreements
In 2019: Charles River signed a binding offer to acquire Citoxlab which would enhance the Company’s ability to partner with clients across the drug discovery and development continuum.
In February 2018: Charles River Laboratories International, Inc. announced a new agreement, which grants Charles River commercial access to AstraZeneca’s high-throughput screening (HTS) and compound management infrastructure.
High Throughput Screening Market Key Developments
• On 22nd August 2021- New high-throughput screening identifies compounds that reduce viability specifically in liver cancer cells that express the high level of sall4 by inhibiting oxidative phosphorylation.
• On 4 Feb 2021- Bio-Rad Laboratories, Inc., showcases new automation features of its ZE5 Cell Analyzer during the Society for Laboratory Automation and Screening 2021 International Conference and Exhibition (SLAs) in Washington, D.C. The ZE5 to be used for high-throughput flow cytometry in biomarker discovery and phenotypic screening. New features offered by the ZE5 help accelerate biopharmaceutical drug discovery, allowing researchers to scale up to multiple assays, such as epitope binding or compound screening assays, when thousands of samples must be analyzed.
• In 2018- The Life Science segment of Bio-Rad Laboratories, Inc., achieved some remarkable product launched with two new chromatographic media for process scale protein purification.
The objective of the report is to present a comprehensive analysis of the Global High Throughput Screening Market including all the stakeholders of the industry. The past and current status of the industry with forecasted market size and trends are presented in the report with the analysis of complicated data in simple language. The report covers all the aspects of the industry with a dedicated study of key players that includes market leaders, followers and new entrants. PORTER, SVOR, PESTEL analysis with the potential impact of micro-economic factors of the market has been presented in the report. External as well as internal factors that are supposed to affect the business positively or negatively have been analysed, which will give a clear futuristic view of the industry to the decision-makers.
The report also helps in understanding Global High Throughput Screening Market dynamics, structure by analysing the market segments and projects the Global High Throughput Screening Market size. Clear representation of competitive analysis of key players by Application, price, financial position, Product portfolio, growth strategies, and regional presence in the Global High Throughput Screening Market make the report investor’s guide.
High Throughput Screening Industry Ecosystem
High Throughput Screening Market Scope: Inquire before buying
| High Throughput Screening Market | |||
|---|---|---|---|
| Report Coverage | Details | ||
| Base Year: | 2023 | Forecast Period: | 2024-2030 |
| Historical Data: | 2018 to 2023 | Market Size in 2023: | USD 25.5 Bn. |
| Forecast Period 2024 to 2030 CAGR: | 10.8% | Market Size in 2030: | USD 52.28 Bn |
| Segments Covered: | by Product and Services | Reagents & Assay Kits Instruments Consumables & Accessories Software Services |
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| by Technology | Cell-based Assays 2D Cell Culture 3D Cell Culture Perfusion Cell Culture Lab-on-a-chip (LOC) Ultra-high-throughput Screening Bioinformatics Label-free Technology |
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| by Application | Target Identification & Validation Primary and Secondary Screening Toxicology Assessment Other Applications |
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| by End-User | Pharmaceutical and Biotechnology Companies Academic and Government Institutes Contract Research Organizations Other |
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High Throughput Screening Market, by Regions
North America (United States, Canada and Mexico)
Europe (UK, France, Germany, Italy, Spain, Sweden, Austria and Rest of Europe)
Asia Pacific (China, South Korea, Japan, India, Australia, Indonesia, Malaysia, Vietnam, Taiwan, Bangladesh, Pakistan and Rest of APAC)
Middle East and Africa (South Africa, GCC, Egypt, Nigeria and Rest of ME&A)
South America (razil, Argentina Rest of South America)
Key Players:
1. Agilent Technologies, Inc
2. Danaher Corporation
3. Perkinelmer, Inc
4. Thermo Fisher Scientific Inc
5. Axxam S.P.A
6. Tecan Group Ltd
7. Bio-Rad Laboratories, Inc
8. Hamilton Company
9. Sigma-Aldrich Corporation
10. Charles River Laboratories International, Inc
11. Merck KGaA
12. Corning Incorporated
13. BioTek Instruments, Inc.
14. Aurora Biomed Inc.
15. General Electric
16. Beckman Coulter, Inc.
17. Luminex Corporation.
18. AstraZeneca
Frequently Asked Questions:
1. Which region has the largest share in Global High Throughput Screening Market?
Ans: North American region holds the highest share in 2023.
2. What is the growth rate of Global High Throughput Screening Market?
Ans: The Global High Throughput Screening Market is growing at a CAGR of 10.8% during forecasting period 2024-2030.
3. What is scope of the Global High Throughput Screening market report?
Ans: Global High Throughput Screening Market report helps with the PESTEL, PORTER, COVID-19 Impact analysis, Recommendations for Investors & Leaders, and market estimation of the forecast period.
4. Who are the key players in Global High Throughput Screening market?
Ans: The important key players in the Global High Throughput Screening Market are – Agilent Technologies, Inc, Danaher Corporation, Perkinelmer, Inc, Thermo Fisher Scientific Inc, Axxam S.P.A, Tecan Group Ltd, Bio-Rad Laboratories.
5. What is the study period of this market?
Ans: The Global High Throughput Screening Market is studied from 2018 to 2030.