Gene Synthesis Market: Global Industry Analysis and Forecast (2022-2029)


Gene Synthesis Market size was valued at US$ 1.60 Bn. in 2021 and the total revenue is expected to grow at 11% through 2021 to 2029, reaching nearly US$ 3.70 Bn.

Gene Synthesis Market Overview:

The synthetic biology process of generating artificial genes in a laboratory setting is known as gene synthesis. At Synbio Technologies, this technology is used to get from a text-based sequence to a physical copy of the genetic sequence with ease and precision. To provide the building blocks for enzymatic assembly, all gene synthesis approaches rely on the chemical synthesis of oligonucleotides. The cyclical four-step phosphoramidite synthesis process devised is the most extensively used method for oligonucleotide synthesis.

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Gene Synthesis Market Dynamics:

Higher R&D in the field of genomics and next-generation sequencing increased government funding for genomics, and rising demand for customized treatment are all factors driving the Gene Synthesis market forward. Personalized medicine has gained popularity in recent years since it strives to give tailored therapies to individual patients based on the biological foundation of disease. Healthcare technologies, genetics, connected devices, big data analytics, and artificial intelligence are all producing massive amounts of health data. This allows healthcare providers to provide more accurate and timely diagnoses, as well as make more educated treatment recommendations.

Factors such as the aging global population and the increased frequency of chronic diseases are putting undue strain on the capacity and financial viability of healthcare systems worldwide. Personalized medicine has the potential to improve patient care and increase safety margins while lowering overall healthcare expenditures. Gene synthesis is also being used in the diagnosis of viral and hereditary illnesses at the molecular level. Commercially available genetic tests that can detect genetic variants and forecast how a person would respond to various medicines are now available. As a result, the gene synthesis industry is growing due to an increased focus on personalized treatment and other reasons such as a patient-centered approach.

Gene Synthesis Market Segment Analysis:

The Custom Gene Synthesis segment is anticipated to adhere to the growth of the Gene Synthesis Market.

The custom gene synthesis segment is likely to dominate the growth of the product type segment in the forecast time frame. The gold standard method for the synthesis of PCR primers is custom gene synthesis, which is derived from oligonucleotide synthesis technology. Gene synthesis is based on this platform and employs exclusive technologies to combine oligos and synthesize a whole gene sequence. Previously, the cost of modified gene synthesis was roughly US$ 0.69/base. Gene synthesis is an effective codon optimization approach for avoiding codon bias during heterologous protein production. Designing DNA sequences with only codons favoured by the desired expression host can greatly boost protein expression. Hence, this factor is likely to boost the growth of the market in the forecast time frame. Moreover, custom gene synthesis is getting more attraction in the field of biotechnology to enhance the treatment of genetic diseases, and vaccines to support public health.

The Industrial and Academic segment is supplementing the growth of the Gene Synthesis Market.

The industrial and Academic segment is projected to boost the growth of the market in the coming future due to Increasing R&D in gene synthesis, as well as ongoing advancement in technological processes like molecular separation and protein purification technologies, which aids in the development of dependable, rapid, and cost-effective solutions. Gene synthesis has progressed in recent years as a result of advances in DNA as a data storage device and re-engineered genomes in the biotechnology industry and Academics. Next-generation gene synthesis allows for the production of extremely precise constructs in higher quantities and at lower prices than previously achievable. Hence, this factor is estimated to lift the growth of the market in the forward direction.

Gene Synthesis Market Regional Insights:

North America currently dominates the gene synthesis market, and this dominance is projected to last for a few more years. The US. has the greatest market share in the North American area. The key causes responsible for the big market include the rising prevalence of genetic and chronic illnesses such as cancer, the aging population, increased need for targeted and customized care, and favorable government efforts. Further, due to rising demand from biopharmaceutical businesses and academic institutions, as well as the presence of a significant number of industry players with a robust distribution channel Twist Bioscience, for example, grew revenue by US$ 68.3 million in 2018 due to the scale-up and commercialization of its silicon chip-based high throughput low-cost gene synthesis platform. Hence, this element further improved the regional market.

The objective of the report is to present a comprehensive analysis of the Gene Synthesis Market to the stakeholders in the industry. The past and current status of the industry with the forecasted market size and trends are presented in the report with the analysis of complicated data in simple language. The report covers all the aspects of the industry with a dedicated study of key players that include market leaders, followers, and new entrants.

PORTER, SVOR, PESTEL analysis with the potential impact of micro-economic factors of the market have been presented in the report. External as well as internal factors that are supposed to affect the business positively or negatively have been analyzed, which will give a clear futuristic view of the industry to the decision-makers.

The report also helps in understanding the Gene Synthesis Market dynamics, structure by analyzing the market segments and project the Gene Synthesis Market size. Clear representation of competitive analysis of key players by Grade, price, financial position, Grade portfolio, growth strategies, and regional presence in the Gene Synthesis Market make the report investor’s guide.

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Global Gene Synthesis Market




Report Coverage
Details




Base Year:
2021
Forecast Period:
2022-2029




Historical Data:
2017 to 2021
Market Size in 2021:
US $ 1.60 Bn.




Forecast Period 2022 to 2029 CAGR:
11%
Market Size in 2029:
US $ 3.70 Bn.




 Segments Covered:
by Product
•Gene library synthesis
•Custom gene synthesis




by End User
• Contract Research Organizations
• Academic and Research Institutes
• Biopharmaceutical Companies




by Application
• Industrial and Academic
• Therapeutics, and Diagnostics






Gene Synthesis Market, by Region

• North America
o US
o Canada
o Mexico
• Europe
o U.K
o France
o Germany
o Italy
o Spain
o Sweden
o CIS Countries
o Rest of Europe
• Asia Pacific
o China
o India
o Japan
o South Korea
o Australia
o ASEAN
o Rest of Asia Pacific
• The Middle East and Africa
o South Africa
o GCC Countries
o Egypt
o Nigeria
o Rest of ME&A
• South America
o Brazil
o Argentina
o Rest of South America

Gene Synthesis Market Key Players

• Thermo Fisher Scientific, Inc.
• Genewiz
• Eurofins Scientific
• ATD Bio Ltd.
• OriGene Technologies, Inc.
• Bioneer Corporation
• Integrated DNA Technologies, Inc
• GenScript Biotech Corporation
• Eurogentec
• General Biosystems
• Twist Bioscience
• Evonetix
• Bio-synthesis Inc
• LGC Limited
• Eurofins Genomics Blue Heron LLC
• Macrogen,Inc
• Science Exchange, Inc
• Integrated DNA Technologies, Inc
• Origene Technologies, INC.
• Proteo Genix
• Biocat GMBH

FAQs:

1. What is the Gene Synthesis Market value in 2021?
Ans: The Gene Synthesis Market value in 2021 was estimated as 1.60 Billion USD.

2. Which End-User segment is likely to dominate the Gene Synthesis Market growth?
Ans: The Contract research Organization segment dominated the market in 2021 and is projected to expand further at the highest CAGR over the forecast period. This can be attributed to Cost effective clinical trials by the organizations and as well as ongoing R&D in the field.

3. Which Region is expected to dominate the Gene Synthesis Market during the forecast period?
Ans: North America dominated the Gene Synthesis market with a share of 36.0% in 2019. This is attributable to the availability of skilled professionals, advanced techniques, and supportive government initiatives in the region.

4. What are the factors driving the Gene Synthesis market?
Ans: Key factors that are driving the market growth include increasing R&D in the field of genomics and next-generation sequencing, the surge in government funding toward genomics, and the growing demand for personalized medicine.

5. Who are the key players in the Gene Synthesis Market?
Ans: Some key players operating in the Gene Synthesis market include Thermo Fisher Scientific, Inc., Genewiz, Eurofins Scientific, ATD Bio Ltd., OriGene Technologies, Inc., Bioneer Corporation, Integrated DNA Technologies, Inc., GenScript Biotech Corporation, and Eurogentec 




1. Preface
1.1. Market Definition and Key Research Objectives
1.2. Research Highlights
2. Assumptions and Research Application
2.1. Report Assumptions
2.2. Abbreviations
2.3. Research Application
2.3.1. Secondary Research
2.3.1.1. Secondary data
2.3.1.2. Secondary Application
2.3.2. Primary Research
2.3.2.1. Data from Primary Application
2.3.2.2. Breakdown of Primary Application
3. Executive Summary: Gene Synthesis Market Size, by Market Value (US$ Bn)
3.1. Global Market Segmentation
3.2. Global Market Segmentation Share Analysis, 2020
3.2.1. Global
3.2.2. By Region (North America, Europe, Asia Pacific, South America, Middle East Africa)
3.3. Geographical Snapshot of the Gene Synthesis Market
3.4. Geographical Snapshot of the Gene Synthesis Market, By Manufacturer share
4. Gene Synthesis Market Overview, 2021-2029
4.1. Market Dynamics
4.1.1. Drivers
4.1.1.1. Global
4.1.1.2. By Region (North America, Europe, Asia Pacific, South America, Middle East Africa)
4.1.2. Restraints
4.1.2.1. Global
4.1.2.2. By Region (North America, Europe, Asia Pacific, South America, Middle East Africa)
4.1.3. Opportunities
4.1.3.1. Global
4.1.3.2. By Region (North America, Europe, Asia Pacific, South America, Middle East Africa)
4.1.4. Challenges
4.1.4.1. Global
4.1.4.2. By Region (North America, Europe, Asia Pacific, South America, Middle East Africa)
4.1.5. Industry Trends and Emerging Technologies
4.1.6. Porter Five Forces Analysis
4.1.6.1. The threat of New Entrants
4.1.6.2. Bargaining Power of Buyers/Consumers
4.1.6.3. Bargaining Power of Suppliers
4.1.6.4. The threat of Substitute Grades
4.1.6.5. The intensity of Competitive Rivalry
4.1.7. Value Chain Analysis
4.1.8. Technological Roadmap
4.1.9. Regulatory landscape
4.1.10. Impact of the Covid-19 Pandemic on the Gene Synthesis Market
5. Supply Side and Demand Side Indicators
6. Gene Synthesis Market Analysis and Forecast, 2021-2029
6.1. Gene Synthesis Market Size & Y-o-Y Growth Analysis.
7. Gene Synthesis Market Analysis and Forecasts, 2021-2029
7.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
7.1.1. Gene library synthesis
7.1.2. Custom gene synthesis
7.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
7.2.1. Industrial and Academic
7.2.2. Therapeutics, and Diagnostics
7.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
7.3.1. Contract Research Organizations
7.3.2. Academic and Research Institutes
7.3.3. Biopharmaceutical Companies
8. Gene Synthesis Market Analysis and Forecasts, By Region
8.1. Market Size (Value) Estimates & Forecast By Region, 2021-2029
8.1.1. North America
8.1.2. Europe
8.1.3. Asia-Pacific
8.1.4. Middle East & Africa
8.1.5. South America
9. North America Gene Synthesis Market Analysis and Forecasts, 2021-2029
9.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
9.1.1. Gene library synthesis
9.1.2. Custom gene synthesis
9.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
9.2.1. Industrial and Academic
9.2.2. Therapeutics, and Diagnostics
9.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
9.3.1. Contract Research Organizations
9.3.2. Academic and Research Institutes
9.3.3. Biopharmaceutical Companies
10. North America Gene Synthesis Market Analysis and Forecasts, By Country
10.1. Market Size (Value) Estimates & Forecast By Country, 2021-2029
10.1.1. US
10.1.2. Canada
10.1.3. Mexico
11. U.S. Gene Synthesis Market Analysis and Forecasts, 2021-2029
11.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
11.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
11.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
12. Canada Gene Synthesis Market Analysis and Forecasts, 2021-2029
12.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
12.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
12.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
13. Mexico Gene Synthesis Market Analysis and Forecasts, 2021-2029
13.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
13.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
13.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
14. Europe Gene Synthesis Market Analysis and Forecasts, 2021-2029
14.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
14.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
14.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
15. Europe Gene Synthesis Market Analysis and Forecasts, By Country
15.1. Market Size (Value) Estimates & Forecast By Country, 2021-2029
15.1.1. U.K
15.1.2. France
15.1.3. Germany
15.1.4. Italy
15.1.5. Spain
15.1.6. Sweden
15.1.7. CIS Countries
15.1.8. Rest of Europe
16. U.K Gene Synthesis Market Analysis and Forecasts, 2021-2029
16.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
16.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
16.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
17. France Gene Synthesis Market Analysis and Forecasts, 2021-2029
17.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
17.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
17.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
18. Germany Gene Synthesis Market Analysis and Forecasts, 2021-2029
18.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
18.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
18.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
19. Italy Gene Synthesis Market Analysis and Forecasts, 2021-2029
19.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
19.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
19.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
20. Spain Gene Synthesis Market Analysis and Forecasts, 2021-2029
20.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
20.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
20.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
21. Sweden Gene Synthesis Market Analysis and Forecasts, 2021-2029
21.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
21.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
21.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
22. CIS Countries Gene Synthesis Market Analysis and Forecasts, 2021-2029
22.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
22.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
22.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
23. Rest of Europe Gene Synthesis Market Analysis and Forecasts, 2021-2029
23.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
23.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
23.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
24. Asia Pacific Gene Synthesis Market Analysis and Forecasts, 2021-2029
24.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
24.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
24.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
25. Asia Pacific Gene Synthesis Market Analysis and Forecasts, by Country
25.1. Market Size (Value) Estimates & Forecast By Country, 2021-2029
25.1.1. China
25.1.2. India
25.1.3. Japan
25.1.4. South Korea
25.1.5. Australia
25.1.6. ASEAN
25.1.7. Rest of Asia Pacific
26. China Gene Synthesis Market Analysis and Forecasts, 2021-2029
26.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
26.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
26.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
27. India Gene Synthesis Market Analysis and Forecasts, 2021-2029
27.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
27.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
27.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
28. Japan Gene Synthesis Market Analysis and Forecasts, 2021-2029
28.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
28.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
28.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
29. South Korea Gene Synthesis Market Analysis and Forecasts, 2021-2029
29.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
29.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
29.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
30. Australia Gene Synthesis Market Analysis and Forecasts, 2021-2029
30.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
30.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
30.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
31. ASEAN Gene Synthesis Market Analysis and Forecasts, 2021-2029
31.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
31.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
31.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
32. Rest of Asia Pacific Gene Synthesis Market Analysis and Forecasts, 2021-2029
32.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
32.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
32.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
33. Middle East Africa Gene Synthesis Market Analysis and Forecasts, 2021-2029
33.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
33.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
33.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
34. Middle East Africa Gene Synthesis Market Analysis and Forecasts, by Country
34.1. Market Size (Value) Estimates & Forecast by Country, 2021-2029
34.1.1. South Africa
34.1.2. GCC Countries
34.1.3. Egypt
34.1.4. Nigeria
34.1.5. Rest of ME&A
35. South Africa Gene Synthesis Market Analysis and Forecasts, 2021-2029
35.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
35.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
35.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
36. GCC Countries Gene Synthesis Market Analysis and Forecasts, 2021-2029
36.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
36.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
36.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
37. Egypt Gene Synthesis Market Analysis and Forecasts, 2021-2029
37.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
37.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
37.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
38. Nigeria Gene Synthesis Market Analysis and Forecasts, 2021-2029
38.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
38.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
38.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
39. Rest of ME&A Gene Synthesis Market Analysis and Forecasts, 2021-2029
39.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
39.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
39.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
40. South America Gene Synthesis Market Analysis and Forecasts, 2021-2029
40.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
40.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
40.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
41. South America Gene Synthesis Market Analysis and Forecasts, by Country
41.1. Market Size (Value) Estimates & Forecast by Country, 2021-2029
41.1.1. Brazil
41.1.2. Argentina
41.1.3. Rest of South America
42. Brazil Gene Synthesis Market Analysis and Forecasts, 2021-2029
42.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
42.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
42.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
43. Argentina Gene Synthesis Market Analysis and Forecasts, 2021-2029
43.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
43.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
43.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
44. Rest of South America Gene Synthesis Market Analysis and Forecasts, 2021-2029
44.1. Market Size (Value) Estimates & Forecast By Product, 2021-2029
44.2. Market Size (Value) Estimates & Forecast By Application, 2021-2029
44.3. Market Size (Value) Estimates & Forecast By End-Use, 2021-2029
45. Competitive Landscape
45.1. Geographic Footprint of Major Players in the Gene Synthesis Market
45.2. Competition Matrix
45.2.1. Competitive Benchmarking of Key Players By Price, Presence, Market Share, Fiber Grades, and R&D Investment
45.2.2. New Grade Launches and Grade Enhancements
45.2.3. Market Consolidation
45.2.3.1. M&A by Regions, Investment, and Verticals
45.2.3.2. M&A, Forward Integration and Backward
Integration
45.2.3.3. Partnership, Joint Ventures, and Strategic Alliances/ Sales Agreements
45.3. Company Profile: Key Players
45.3.1. Merck & Co., Inc.
45.3.1.1. Financial Overview
45.3.1.2. Geographic Footprint
45.3.1.3. Grade Portfolio
45.3.1.4. Business Strategy
45.3.1.5. Recent Developments
45.3.2. Thermo Fisher Scientific, Inc.
45.3.3. Genewiz
45.3.4. Eurofins Scientific
45.3.5. ATD Bio Ltd.
45.3.6. OriGene Technologies, Inc.
45.3.7. Bioneer Corporation
45.3.8. Integrated DNA Technologies, Inc
45.3.9. GenScript Biotech Corporation
45.3.10. Eurogentec
45.3.11. General Biosystems
45.3.12. Twist Bioscience
45.3.13. Evonetix
45.3.14. Bio-synthesis Inc
45.3.15. LGC Limited
45.3.16. Eurofins Genomics Blue Heron LLC
45.3.17. Macrogen,Inc
45.3.18. Science Exchange, Inc
45.3.19. Integrated DNA Technologies, Inc
45.3.20. Origene Technologies, INC.
45.3.21. Proteo Genix
45.3.22. Biocat GMBH
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