Hollow Fiber Filtration Companies: Repligen Corporation, GE Healthcare, and Parker Hannifin Corporation

The Hollow Fiber Filtration Companies are prominently investing in R&D, portfolio optimization, and strategic management of key accounts to meet the specific quality needs of customers. Hollow Fiber Filtration Manufacturers are differentiating themselves through continuous product launches, expanding their presence in new modalities in water treatment, and bioprocessing. Hollow fiber membranes, known for their cost-effectiveness and versatility, are widely used in applications ranging from groundwater filtration to treating highly polluted wastewater. The inside-out configuration of these membranes offers ease in integrity testing, making them a preferred solution for water, beer, and wine filtration. Leading players focus on expanding opportunities through tailored solutions, aiming to inspire advances in bioprocessing and maintain competitiveness in the evolving Hollow Fiber Filtration Industry with mergers and acquisitions.

Hollow Fiber Filtration Companies are focusing on developing high-performance filtration systems that enhance productivity, efficiency, and flexibility in manufacturing. Continuous processing technologies offer significant advantages over traditional batch methods, including faster cell isolation, reduced manufacturing times, and improved safety profiles. The competition is driven by the need for customizable filtration solutions, with various specifications and formats available to optimize bioprocessing. Partnerships between technology developers and filtration system providers are common, as they allow for the integration of cutting-edge filtration technologies into established manufacturing platforms. This dynamic environment fosters competition, where Hollow Fiber Filtration companies aim to meet the emerging demands of biopharmaceutical manufacturers by offering advanced filtration systems that support scalable, efficient, and compliant bioprocessing solutions.

The Hollow Fiber Filtration Market size was valued at USD 352.12 Million in 2023 and is expected to grow from 2024 to 2030, reaching nearly USD 919.68 Million by 2030. Hollow fiber filtration is a pivotal technology in the biopharmaceutical and water treatment industries, characterized by its unique structure and operational benefits. The technology utilizes hollow fiber membranes, which feature a smooth internal wall and tubular channel geometry, promoting laminar flow with high flux. This design minimizes shear and turbulence, making it ideal for handling shear-sensitive materials such as lentivirus and other delicate biopharmaceuticals. Hollow fiber filtration companies offer several features with high efficiency, scalability, and the ability to achieve high product purity. Company Profile Analysis for Hollow Fiber Filtration Market: The Hollow Fiber Filtration Market is highly competitive, featuring key players such as Repligen Corporation, GE Healthcare, Parker Hannifin Corporation, and Koch Membrane Systems. Repligen Corporation, based in Waltham, Massachusetts, is known for its Spectrum Hollow Fiber Filters, which excel in ultrafiltration and microfiltration, particularly for shear-sensitive modalities. Their filters, utilizing advanced mPES membrane chemistry, offer high selectivity, reduced fouling, and efficient processing, making them suitable for applications such as lentivirus and mRNA which drives the growth in market share of Hollow Fiber Filtration companies. Repligen Corporation: Repligen Corporation’s Spectrum Hollow Fiber Filters excel in ultrafiltration and microfiltration, particularly for shear-sensitive modalities. These filters are designed to handle a wide range of scales, membrane chemistries, and pore sizes, enhancing process outcomes. Their mPES membrane chemistry, derived from PES, offers high selectivity and flux, ideal for applications such as lentivirus, mRNA, pDNA, and LNPs to strengthen the portfolio. The smooth internal wall and laminar flow of the hollow fibers help maintain the integrity of delicate molecules by minimizing shear and turbulence with capex investment wave. Repligen emphasizes efficiency with a robust supply chain, high automation facilities, and competitive lead times to Hollow Fiber Filtration capitalize on the growth of the market. Their filters are available in various configurations and equipped with or without gamma irradiation. This commitment to innovation and quality positions Repligen as a leader in advanced bioprocessing solutions. Asahi Kasei Corporation Asahi Kasei's hollow fiber membrane technology development began in the 1970s, and by the 1980s, the company started marketing these membranes under the Microza brand. Today, Microza is utilized for purification and concentration across various industries, including water treatment, chemicals, food, and pharmaceuticals. Headquartered in Tokyo, we continue to serve customers globally, addressing their diverse needs. In April 2024, Asahi Kasei launched a new membrane system for producing Water for Injection (WFI), a sterile water used in injections. This innovative system, developed as an alternative to traditional distillation methods, utilizes the Microza™ hollow-fiber membrane technology. By leveraging advanced system design and development, the new system reduces steam generation, resulting in lower CO2 emissions and reduced production costs for WFI. This development reflects Asahi Kasei's commitment to improving efficiency and sustainability in water treatment and filtration processes for liquid products. Recent Development

• On October 5, 2023, Evonik, a leader in speciality chemicals, enhanced its production capabilities for SEPURAN hollow fiber membranes by expanding facilities in Schörfling and Lenzing, Austria. Earlier in 2023, Evonik inaugurated a new hollow fiber spinning plant in Schörfling.

• In April 2022, Ferring Pharmaceuticals, a global pharmaceutical company, launched an integrated R&D and manufacturing facility in Hyderabad with a US$ 30 million investment. This growth in the pharmaceutical sector, driven by advancements in formulation, packaging, and analytical techniques, is fueling the increased adoption of hollow fiber filtration for product purification. This trend is positively impacting the hollow fiber filtration market segment.

1. Hollow Fiber Filtration Market Competition Matrix 2. Key Players Benchmarking • Company Name • Product Segment • End User Segment • Revenue • Manufacturing Locations 3. Mergers and Acquisition 4. Market Structure of Companies • Market Leaders • Market Followers • Emerging Players 5. Hollow Fiber Filtration Market Manufacturing Company Profile: Key Players 5.1. Repligen Corporation (Waltham, Massachusetts, USA) • Company Overview • Business Portfolio • Financial Overview • SWOT Analysis • Strategic Analysis • Recent Developments 5.2. GE Healthcare (Chicago, Illinois, USA) 5.3. Parker Hannifin Corporation (Cleveland, Ohio, USA) 5.4. Koch Membrane Systems (Wilmington, Massachusetts, USA) 5.5. Asahi Kasei Corporation (Tokyo, Japan) 5.6. Sartorius AG (Göttingen, Germany) 5.7. Merck KGaA (Darmstadt, Germany) 5.8. Danaher Corporation (Washington, D.C., USA) 5.9. Pentair plc (London, United Kingdom) 5.10. Pall Corporation (Port Washington, New York, USA) 5.11. Fujifilm Diosynth Biotechnologies (Billingham, United Kingdom) 5.12. Spectrum Laboratories, Inc. (Rancho Dominguez, California, USA) 5.13. Watersep Bioseparation Corporation (Marlborough, Massachusetts, USA) 5.14. Meissner Filtration Products, Inc. (Camarillo, California, USA) 5.15. Novasep Holding SAS (Lyon, France) 5.16. TangenX Technology Corporation (Shrewsbury, Massachusetts, USA) 5.17. Sysbiotech GmbH (Vienna, Austria) 5.18. Cobetter Filtration Equipment Co., Ltd. (Hangzhou, China) 5.19. Xenith Labs (Singapore) 5.20. Avidity Science (Waterford, Wisconsin, USA)