Synthetic Biology Market was valued at US$ 9.6 Bn in 2021 and is expected to reached at US$ 51.2 Bn in 2029. Synthetic Biology Market size is expected to grow at a CAGR of 27.02% through the forecast period.
Synthetic Biology Market Overview:Synthetic biology (SynBio) is a multidisciplinary field of study that aims to develop new biological components, gadgets, and systems and remodel existing natural systems. It is a branch of science that includes numerous methodologies from different fields, including biotechnology, genetic engineering, molecular biology, molecular engineering, systems biology, membrane science, biophysics, chemical and biological engineering, electrical and computer engineering, control engineering, and evolutionary biology. To know about the Research Methodology:-Request Free Sample Report The main objective is to create fully operational biological systems from the smallest constituent parts possible, including DNA, proteins, and other organic molecules. Synthetic biology incorporates many different scientific techniques and approaches. Synthetic biology covers a broad research area, which combines the disciplines of biology and engineering to design and create new biological systems to perform functions that are not found in nature. The report explores the Synthetic Biology Market segments (Product Type, Application, Technology, End-users and Region). Data has been provided by market participants, and regions (North America, Asia Pacific, Europe, Middle East & Africa, and South America). The MMR market report provides a thorough analysis of the rapid advances that are currently taking place across all industry sectors. Facts and figures, illustrations, and presentations are used to provide key data analysis for the historical period from 2017 to 2020. The report investigates the Synthetic Biology Market drivers, limitations, prospects, and barriers. This MMR report includes investor recommendations based on a thorough examination of the Synthetic Biology Market contemporary competitive scenario. 2021 is considered as a base year to forecast the market from 2022 to 2029. 2021’s market size is estimated on real numbers and outputs of the key players and major players across the globe. Past five years' trends are considered while forecasting the market through 2029. 2020 is a year of exception and analysis especially with the impact of lockdown by region.
Synthetic Biology Market Dynamics:Market Drivers: The increased funding for research and development in synthetic biology is the major factor which drives the growth of the Synthetic Biology Market. Pharmaceutical companies now receive more funds for research and development to create new therapies. Government measures to fund various pharma and biotech enterprises have taken nutraceutical research and boosted meditativeness. Pharmaceutical and biotechnology businesses make significant investments in research to create ground-breaking compounds that will meet the expanding demands of the healthcare sector and find cures for novel diseases. Extensive range of applications of synthetic biology is expected to boost the market growth. Products derived from synthetic biology techniques are used in a variety of sectors such as bioenergy, enzyme technology, biology-based chemicals, antibody production, vaccine manufacturing, among others. Increasing global population and scarcity of essential resources have propelled several research and development activities in the food & nutrition space. Here, synthetic biology has aided in identification of sustainable food production systems. The technique has also contributed in attaining improved food yields and better management of pest control. The growing involvement of government bodies, research institutes, and large organizations in synthetic biology research activities are the factors which is likely to rise the growth of the Synthetic Biology Market. Synthetic biology technologies and products are also finding significant usage in various application areas. Since the organisms engineered with synthetic biology techniques are relatively reasonable, owing to their use in various industrial applications, which also translates into a reduction in the cost of research, the demand for these techniques is growing worldwide. Market Restraints: The biosafety and biosecurity of developing synthetic biological products and the ethical issues will hinder the growth of the Synthetic Biology Market. It is not hard to see why some artificial biological products may fail to fit into the accurate dichotomy between living and non-living. Such concerns restrain the research and development and, in turn, the market’s growth. The deliberate or accidental release of synthetic organisms into the environment for research and other reasons is the main biosafety problem in synthetic biology. The development of synthetic biology products has raised many concerns related to biosafety and biosecurity. Exposure to these products may cause unknown hazards to public health and the environment. When artificial microorganisms are released into the environment, they have the potential to mutate or interact with other organisms, which could lead to cross-breeding with real creatures and the development of bio mistakes. The ecosystem of living things may be in danger as a result of these effects. A significant biosafety problem is the development of superbugs resistant to antibiotics. The European Union (EU) has recently supported several studies on the environmental effects of intentionally releasing genetically modified microorganisms for plant growth or bioremediation. These elements could limit market growth in the ensuing years. Market Opportunities: Due to rising fuel usage and growing worries about the security of the energy supply, biofuels are becoming increasingly important. Over 150 billion tonnes of biomass are produced annually on a scale. At the moment, biofuels are made using food products like maize, sugarcane, and vegetable oil. In turn, this is opening the door for the use of synthetic biology methods in the creation of renewable energy. This is the opportunity which helps to drive the Synthetic Biology Market. There is a significant rise in the use of genetically engineered viruses to correct defective genes in patients with inherited diseases like epidermolysis bullosa or severe combined immune deficiency (SCID). rising funding opportunities and assistance from government and private organizations is anticipated to positively affect the market growth. The rising demand for bio-fuels, growing awareness in emerging economies and rising R&D investments for synthetic drugs and vaccines would offer the opportunities in the market. Market Challenges: The Issue with process and recycling are the major challenges which are faced during the growth of the Synthetic Biology Market. Synthetic biology can manage environmental challenges such as climate change, natural resources management, and pollution reduction. The technique can be combined with genetic engineering for creation of microorganisms that serve as biosensors for detecting toxic environmental contaminants. The issues related to the misuse of synthetic biology or possibilities of accidental release of pathogens into free atmosphere is a key challenge during the growth of the Synthetic Biology Market. COVID-19 Impact on Synthetic Biology Market: During the COVID-19 pandemic, the market had a slight decline in growth due to decreasing production, followed by lockdown and lack of labour situation. The prices were higher than usual. Due to the increasing demand for innovation and development of vaccines, therapeutics, and diagnostics, the synthetic biology market had a positive impact on the market. This played a major role in increasing the revenue of the studied market. The ongoing research for COVID vaccine and drugs furthermore boosts the market growth. By supplying synthetic biology for creating test kits, medications, and vaccinations to support international research initiatives that specifically target the coronavirus infection, many well-known pharmaceutical and biopharmaceutical businesses, as well as market participants were stepped out. In a study from the European Parliament, synthetic biology is identified as one of the rising technologies. It can combat COVID-19. The US National Institute of Health has also mentioned synthetic biology as a means of accelerating vaccine development. By employing their engineering methods founded on a range of information (genomic sequences, sequence annotations, enzyme characteristics, etc.), synthetic biology technologies have the potential to revolutionize the creation and manufacture of vaccines, treatments, and diagnostics. Recent Developments: • In January 2021, Novozymes launched Frontia GlutenEx. It would help wheat processors increase their gluten protein recovery and, at the same time, cut down on energy consumption. • In February 2021, Merck partnered with BioNTech (Germany) to supply lipids for the production of Pfizer-BioNTech COVID-19 Vaccine (BNT162b2). • In January 2021, Merck acquired AmpTec (Germany). With this acquisition, the company strengthened its product portfolio to develop and manufacture mRNA for utilizing vaccines, treatments, and diagnostics. • In January 2021, AbSci, one of the leading synthetic biology companies enabling drug discovery and biomanufacturing of next-generation biotherapeutics, announced the acquisition of Denovium Inc., an artificial intelligence (AI) deep learning company. This acquisition represents the perfect synergy of groundbreaking synthetic biology and cutting-edge deep learning AI to create in silico predictive protein drug design and cell line development capabilities with the potential to completely change the paradigm of biopharmaceutical discovery and development. • On November 30, 2021, GenScript expanded its gene synthesis manufacturing capabilities in the United States with fully automated oligo synthesis and sequencing platforms. • On January 31, 2022, Ribbon Biolabs, a DNA synthesis company, raised a EUR 18 million series A financing fund. The company enabled commercial-scale production facilities and the United States expansion for DNA synthesis technology with this fund.
Synthetic Biology Market Segment Analysis:Based on Type, the segment Oligonucleotide/oligo pools and synthetic DNA is considered to be the highest market with CAGR of XX% during the forecast period. The ability to design custom DNA oligos for experiments has created ample opportunities in the fields, such as molecular and synthetic biology. The amount of any given oligonucleotide consumed in the process of gene synthesis is minimal, typically in the mid-picomole range. This is because in vitro assembly of DNA oligonucleotides involve a DNA amplification phase after chemical synthesis. The decreasing cost of synthesis and rising demand for synthetic DNA, RNA, and genes that are used in various applications leas to the growth of the Oligonucleotide/oligo pools and synthetic DNA segment in Synthetic Biology Market. The enzymes segment is also estimated to grow with the highest market share in 2021. Companies are focusing on the efficient, cost-effective, and eco-friendly production of enzymes which leads to the increasing demand for the Synthetic Biology Market. Many companies are focusing on the adoption of enzymatic chemistry rather than existing phosphonamidite chemistry for gene synthesis. The potential application of enzymatic synthesis to deliver longer genes in the shortest turnaround time will boost industry growth. These all factors lead to the growth of the Synthetic Biology Market. Based on the Application, the healthcare segment is dominating the market with XX% share in 2021. Synthetic biology has offered significant advancements in the scale and scope of biopharmaceutical drug development. The technology offers actionable solutions to overcome the limitations associated with current biopharma production for gene design, expression optimization, yield stability, fermentation, and purification. Diagnostics based on synthetic biology provide a real-time, specific & sensitive, and non-invasive process which helps for detecting cancer cells, infectious agents, and therapeutics. Glympse Bio has manufactured an activity-based biosensor to diagnose the early signs of Non-Alcoholic Steatohepatitis (NASH), predict the stage of disease, and support drug development. These all factors drive the growth of the market. Bio-fuels in the non-healthcare segment is considered to be the largest revenue-generating sub-segment. Synthetic biology has created the possible way for the fourth generation of biofuels. As these are expected to have the potential to reduce Greenhouse Gas (GHG) emissions, the researchers are involved in developing alternative biofuel molecules. Companies, such as GenScript, offer GenPlus high-throughput gene synthesis, combinatorial assembly library, and CRISPR/Cas9 genome editing for biofuel production. Based on Technology, The PCR technology segment accounted for the largest market share of XX% in 2021 due to the high usage of this technology as it is fast, convenient, easily reproducible, extremely specific, and highly sensitive. PCR cloning is applied to gene cloning, DNA recombination, and gene quantification in synthetic biology workflows. Syno 2.0 platform offered by Synbio Technologies which can efficiently clone target genes without relying on the restriction enzyme sites. The development and launch of such platforms enhance the cost-effectiveness of PCR in synthetic biology applications and leads to the growth of the Synthetic Biology Market. The NGS technology segment is expected to be the second-fastest growing market with highest CAGR during the forecast period. The ability of NGS to synthesize DNA sequences from the start, along with new technologies, such as CRISPR/Cas9, is enabling the targeted introduction of DNA sequences into living cells. Application in the field of rapid whole-genome sequencing, deeply sequences target regions, discovering novel RNA, understanding of the human microbiome, and identification of novel pathogens. Based on End-User, The biotechnology and pharmaceutical companies segment dominated the market with a highest market share in 2021. Synthetic biology has helped biotechnology and pharmaceutical companies to develop novel drugs, which can treat chronic conditions. For instance, Merck has used synthetic biology approaches to develop Januvia (sitagliptin) for diabetes patients. Similarly, Novartis developed Kymriah (Tisagenlecleucel) to treat B-cell acute lymphoblastic leukemia. Furthermore, various companies have used synthetic biology to engineer pathways that enable microorganisms to produce medically relevant drugs. For instance, Amyris Inc. engineered yeast strains to develop the antimalarial drug Artemenisin. Moreover, synthetic biology can also improve in-vitro drug production. For instance, Codexis utilizes synthetic biology to develop a more efficient enzyme for the synthesis of small-molecule drugs.
Synthetic Biology Market Regional Insights:The North America region is expected to witness significant growth at a CAGR of XX% through the forecast period because of the increased investment in the creation of synthetic biology products, advantageous legislation, and government support. In the first half of 2020, startups in this market raised more than $3 billion in funding, including Moderna Therapeutics, Sana Biotechnology, Poseida Therapeutics, Apeel Sciences, and Greenlight Biosciences. The U.S. places a lot of emphasis on research in the fields of proteomics, genomic structure expectation, and drug development, which has a positive impact on the synthetic biology market. Additionally, several privately held companies like the Gates and Melinda Foundation and publicly financed research institutions like the National Institutes of Health (NIH) are promoting research and development in synthetic biology, which could improve the country's market prospects. The dominance is attributed to various factors such as the increase in the number of well-established synthetic biology companies and research institutes in the US and Canada. Huge ongoing research studies and growth of the overall healthcare sector are additional factors expected to impact the growth of this market. Substantial R&D spending is one of the key factors contributing to the increasing demand for synthetic biology tools and technologies among academic & research institutes and healthcare companies in North America. The objective of the report is to present a comprehensive analysis of the Synthetic Biology Market to the stakeholders in the industry. The past and current status of the industry with the forecasted market size and trends are presented in the report with the analysis of complicated data in simple language. The report covers all the aspects of the industry with a dedicated study of key players that include market leaders, followers, and new entrants. PORTER, PESTEL analysis with the potential impact of micro-economic factors of the market have been presented in the report. External as well as internal factors that are supposed to affect the business positively or negatively have been analyzed, which will give a clear futuristic view of the industry to the decision-makers. The reports also help in understanding the Synthetic Biology Market dynamic, structure by analyzing the market segments and projecting the Synthetic Biology Market size. Clear representation of competitive analysis of key players by Vehicle type, price, financial position, product portfolio, growth strategies, and regional presence in the Synthetic Biology Market make the report investor’s guide.
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Global Synthetic Biology Market Report Coverage Details Base Year: 2021 Forecast Period: 2022-2029 Historical Data: 2017 to 2021 Market Size in 2021: US$ 9.6 Bn. Forecast Period 2022 to 2029 CAGR: 27.02% Market Size in 2029: US$ 51.2 Bn. Segments Covered: by Product Type • Oligonucleotides and Synthetic DNA • Enzymes • Cloning Technologies Kits • Synthetic Cells • Chassis Organisms • Xeno-nucleic Acids by Application • Healthcare o Clinical o Bio/Pharmaceuticals o Diagnostics o Non-Clinical/Research • Non-Healthcare o Biotech Crops o Specialty Chemicals o Bio-Fuels o Others by Technology • NGS • PCR • Genome Editing • Bioprocessing Technology • Others by End-User • Biotechnology & Pharmaceutical Companies • Academic & Government Research Institutes • Others
Synthetic Biology Market by Region• North America • Europe • Asia Pacific • South America • Middle East and Africa
Synthetic Biology Market Key Players• Thermo Fischer Scientific • GenScript, DNA2.0 • Integrated DNA technologies • Eurofins Scientific, Inc. • Origene technologies • Scientific genomics Inc • Editas Medicine, Inc. • Pareto Biotechnologies • Blue heron • TeselaGen • Bota Biosciences • Codexis, Inc. • Creative Biogene • Creative Enzymes • EnBiotix, Inc. • Eurofins Scientific • Royal DSM • Merck KGaA • Agilent Technologies • Novozymes • Ginkgo Bioworks • Amyris • Precigen, Inc. • Twist Bioscience • Synthetic Genomics • Synthego Frequently Asked Questions: 1] What segments are covered in the Synthetic Biology Market report? Ans. The segments covered in the Synthetic Biology Market report are based on Product Type, Technology, End-User and Application. 2] Which region is expected to hold the highest share in the Synthetic Biology Market? Ans. North America region is expected to hold the highest share in the Synthetic Biology Market. 3] What is the market size of the Synthetic Biology Market by 2029? Ans. The market size of the Synthetic Biology Market by 2029 is expected to reach US$ 51.2 Bn. 4] What is the forecast period for the Synthetic Biology Market? Ans. The forecast period for the Synthetic Biology Market is 2021-2029. 5] What was the market size of the Synthetic Biology Market in 2021? Ans. The market size of the Synthetic Biology Market in 2021 was valued at US$ 9.6 Bn.
1. Synthetic Biology Market: Research Methodology 2. Synthetic Biology Market: Executive Summary 2.1. Market Overview and Definitions 2.1.1. Introduction to Synthetic Biology Market 2.2. Summary 2.2.1. Key Findings 2.2.2. Recommendations for Investors 2.2.3. Recommendations for Market Leaders 2.2.4. Recommendations for New Market Entry 3. Synthetic Biology Market: Competitive Analysis 3.1. MMR Competition Matrix 3.1.1. Market Structure by region 3.1.2. Competitive Benchmarking of Key Players 3.2. Consolidation in the Market 3.2.1 M&A by region 3.3. Key Developments by Companies 3.4. Market Drivers 3.5. Market Restraints 3.6. Market Opportunities 3.7. Market Challenges 3.8. Market Dynamics 3.9. PORTERS Five Forces Analysis 3.10. PESTLE 3.11. Regulatory Landscape by region • North America • Europe • Asia Pacific • The Middle East and Africa • South America 3.12. COVID-19 Impact 4. Synthetic Biology Market Segmentation 4.1. Synthetic Biology Market, By Product Type (2021-2029) • Oligonucleotides and Synthetic DNA • Enzymes • Cloning Technologies Kits • Synthetic Cells • Chassis Organisms • Xeno-nucleic Acids 4.2. Synthetic Biology Market, By Application (2021-2029) • Healthcare o Clinical o Bio/Pharmaceuticals o Diagnostics o Non-Clinical/Research • Non-Healthcare o Biotech Crops o Specialty Chemicals o Bio-Fuels o Others 4.3. Synthetic Biology Market, By Technology (2021-2029) • NGS • PCR • Genome Editing • Bioprocessing Technology • Others 4.4. Synthetic Biology Market, By End-User (2021-2029) • Biotechnology & Pharmaceutical Companies • Academic & Government Research Institutes • Others 5. North America Synthetic Biology Market (2021-2029) 5.1. North America Synthetic Biology Market, By Product Type (2021-2029) • Oligonucleotides and Synthetic DNA • Enzymes • Cloning Technologies Kits • Synthetic Cells • Chassis Organisms • Xeno-nucleic Acids 5.2. North America Synthetic Biology Market, By Application (2021-2029) • Healthcare o Clinical o Bio/Pharmaceuticals o Diagnostics o Non-Clinical/Research • Non-Healthcare o Biotech Crops o Specialty Chemicals o Bio-Fuels o Others 5.3. North America Synthetic Biology Market, By Technology (2021-2029) • NGS • PCR • Genome Editing • Bioprocessing Technology • Others 5.4. North America Synthetic Biology Market, By End-User (2021-2029) • Biotechnology & Pharmaceutical Companies • Academic & Government Research Institutes • Others 5.5. North America Synthetic Biology Market, by Country (2021-2029) • United States • Canada • Mexico 6. European Synthetic Biology Market (2021-2029) 6.1. European Synthetic Biology Market, By Product Type (2021-2029) 6.2. European Synthetic Biology Market, By Application (2021-2029) 6.3. European Synthetic Biology Market, By Technology (2021-2029) 6.4. European Synthetic Biology Market, By End-User (2021-2029) 6.5. European Synthetic Biology Market, by Country (2021-2029) • UK • France • Germany • Italy • Spain • Sweden • Austria • Rest Of Europe 7. Asia Pacific Synthetic Biology Market (2021-2029) 7.1. Asia Pacific Synthetic Biology Market, By Product Type (2021-2029) 7.2. Asia Pacific Synthetic Biology Market, By Application (2021-2029) 7.3. Asia Pacific Synthetic Biology Market, By Technology (2021-2029) 7.4. Asia Pacific Synthetic Biology Market, By End-User (2021-2029) 7.5. Asia Pacific Synthetic Biology Market, by Country (2021-2029) • China • India • Japan • South Korea • Australia • ASEAN • Rest Of APAC 8. Middle East and Africa Synthetic Biology Market (2021-2029) 8.1. Middle East and Africa Synthetic Biology Market, By Product Type (2021-2029) 8.2. Middle East and Africa Synthetic Biology Market, By Application (2021-2029) 8.3. Middle East and Africa Synthetic Biology Market, By Technology (2021-2029) 8.4. Middle East and Africa Synthetic Biology Market, By End-User (2021-2029) 8.5. Middle East and Africa Synthetic Biology Market, by Country (2021-2029) • South Africa • GCC • Egypt • Nigeria • Rest Of ME&A 9. South America Synthetic Biology Market (2021-2029) 9.1. South America Synthetic Biology Market, By Product Type (2021-2029) 9.2. South America Synthetic Biology Market, By Application (2021-2029) 9.3. South America Synthetic Biology Market, By Technology (2021-2029) 9.4. South America Synthetic Biology Market, By End-User (2021-2029) 9.5. South America Synthetic Biology Market, by Country (2021-2029) • Brazil • Argentina • Rest Of South America 10. Company Profile: Key players 10.1 Thermo Fischer Scientific 10.1.1. Company Overview 10.1.2. Financial Overview 10.1.3. Global Presence 10.1.4. Capacity Portfolio 10.1.5. Business Strategy 10.1.6. Recent Developments 10.2. GenScript, DNA2.0 10.3. Integrated DNA technologies 10.4. Eurofins Scientific, Inc. 10.5. Origene technologies 10.6. Scientific genomics Inc 10.7. Editas Medicine, Inc. 10.8. Pareto Biotechnologies 10.9. Blue heron 10.10. TeselaGen 10.11. Bota Biosciences 10.12. Codexis, Inc. 10.13. Creative Biogene 10.14. Creative Enzymes 10.15. EnBiotix, Inc. 10.16. Eurofins Scientific 10.17. Royal DSM 10.18. Merck KGaA 10.19. Agilent Technologies 10.20. Novozymes 10.21. Ginkgo Bioworks 10.22. Amyris 10.23. Precigen, Inc. 10.24. Twist Bioscience 10.25. Synthetic Genomics 10.26. Synthego