Single-use Bioprocessing Market size was valued at USD 11.97 Bn. in 2022 and the total Single-use Bioprocessing revenue is expected to grow by 21 % from 2023 to 2029, reaching nearly USD 45.6 Bn.
Single-use Bioprocessing Market Overview:The Single-use systems are pieces of biopharmaceutical production (bioprocessing) equipment that are intended to be used once and then discarded. Single-use system equipment is often constructed of plastic components that have been disinfected and sealed using gamma irradiation. The global Single-use Bioprocessing Market growth is primarily attributed to the increased biologics demand. Single-use containers are commonly employed for essential liquid handling applications in the biomanufacturing and biopharmaceutical industries. As compared to its market over a decade ago, the adoption of single-use bioprocessing equipment has experienced a significant shift in recent years. Single-use bioprocessing systems are primarily used to avoid hospital-acquired infections. Single-use bioprocessing systems enable biopharmaceutical companies to undertake rapid R&D and pilot studies while saving money on capital.
Report Scope:The report covers market features, size, growth, segmentation, geographical breakdowns, market shares, trends, and plans for the business on both the demand and supply sides. A forecast of the market is mainly presented based on factors on which the companies contribute to the market estimation, key trends, and segmentation analysis. It covers effective business strategies, consumer preferences, governmental regulations, recent competitor actions, as well as future business prospects and market concerns. In-depth financial information about top manufacturers, such as year-after-year sales, revenue growth, CAGR, production cost analysis, and value chain structure, is highlighted in the Single-use Bioprocessing Market report. To know about the Research Methodology :- Request Free Sample Report
Single-use Bioprocessing Market Dynamics:Market Drivers: The growth in the biopharmaceuticals industry Faster implementation and decreased risk of product cross-contamination, increased demand for biopharmaceuticals, cheaper prices, and lower environmental effects of single-use bioprocessing technologies are driving the single-use bioprocessing market growth. With a growing need for biopharmaceuticals owing to an increase in the number of chronic diseases among the population, there is a greater need for effective treatments and goods, which is expected to raise demand for single-use technologies, boosting the single-use bioprocessing industry growth. According to the Food and Drug Administration, 14 biologics will be authorized for the treatment of various chronic conditions in 2022. As a result, the increasing number of biological approvals is expected to boost the biopharmaceutical production process, resulting in increased usage and acceptance of single-use bioprocessing technologies and systems during the forecast period. Additionally, single-use technologies and systems assist biopharmaceutical firms in decreasing contamination hazards and reducing the requirement for sterilizing between batches, hence enhancing efficiency. Moreover, firms are concentrating on building a new single-use system that will be used in both upstream and downstream processing of biopharmaceutical manufacturing. The product's low water consumption, good energy efficiency, small footprint, and little danger of contamination are all elements driving single-use bioprocessing growth. Additionally, the adoption of big data-based machine learning in single-use systems, which aids in increasing product or drug yield and achieving maximum productivity and efficiency in terms of process, along with a mainstream strategy by biopharmaceutical manufacturers, are all contributing to the growth of the single-use bioprocessing market. In addition, the growing corporate activities and increased adoption of different business strategies such as collaborations, partnerships, and product launches are adding to market growth. For example, Qosina signed a distribution deal with Nordson MEDICAL in May 2021 to help Single-Use Bioprocess Integrators and Medical Device Manufacturers. Growing demand for single-use bioprocessing The benefits of Single-Usage Technology (SUT), such as considerable capital cost and facility-building time savings, have increased the use of disposables in the bioprocessing sector. As a result, the market for single-use bioprocessing has grown by double digits. Additionally, despite the global economic loss caused by the COVID-19 epidemic, the market appreciated tremendous growth. Several CMOs and biomanufacturers have turned their commercial focus to the development of SARS-CoV-2 infection treatments employing disposable technology. Serum Institute chose ABEC's Custom Single Run (CSR) technology in September 2020 to speed the large-scale, single-use manufacture of roughly 1.5 billion doses of the Novavax vaccine against COVID-19. The ability of consumers to make adjustments and purchase single-use products based on their own customization promotes the single-use bioprocessing market growth. Depending on the application, bioreactors and single-use bags and containers can all be customized to meet the needs of the customer. The number of therapeutic antibody candidates under phase 3 clinical development in the United States has nearly doubled in the last five years, reaching more than 50. Single-use technologies are quickly becoming popular in several application areas. As a result, growth in monoclonal antibody and vaccine manufacturing is expected to fuel the single-use bioprocessing market growth. Market Restraints: Concerns with leachables and extractables There are no specific rules or regulations in place regulating the contamination of single-use bioprocessing systems owing to extractables and leachables. The Single-use Bio-Process Systems Alliance, on the other hand, has provided a comprehensive list of tests that may be done on single-use systems (BPSA). Under rigorous laboratory settings, extractables can be extracted from source materials using suitable solvents. Simultaneously, leachables are substances found in medicinal products as a result of leaching from containers, closures, and manufacturing components. As a result, leachables may be thought of as a subset of extractable. These leachables and extractables are undesirable. Because single-use bioprocessing items are composed of processed plastic materials, they are frequently contaminated by leachables from the container. As a result, major concerns about extractables and leachables derived from single-use bioprocessing system components are expected to impede single-use bioprocessing market growth owing to their possible implications on product quality and patient health. Market Opportunities: Growing Investment in Emerging Markets China is the most promising market in the APAC region for single-use bioprocessing systems, followed by India. The growth is attributed to the availability of favorable government backing, growing private investments, a growing senior population, a rising tendency of outsourcing to burgeoning Asian markets, and the presence of a qualified workforce in these countries. Additionally, considerable investment in bio-manufacturing infrastructure is a crucial aspect contributing to these sectors' strong development potential. For example, in March 2021, Thermo Fisher Scientific announced a USD 605 million investment to increase its bioprocessing capabilities. This investment was made to accommodate the growing demand for vaccination and biologics manufacturing. Several end-users regard single-use systems (SUS) to be an economically feasible way to achieve optimum process efficiency and productivity. As a result, SUS equipment is widely used throughout the biomanufacturing process, notably in pre-commercial biopharmaceutical production. This has produced opportunities for the space's product suppliers. Additionally, one of the primary reasons driving the single-use bioprocessing market is the growing number of suppliers supplying robust disposables for the commercial synthesis of biopharmaceuticals. Additionally, the development of automation in the bioprocessing business has drastically increased biomanufacturing efficiency. Big data analytics is expected to be a prominent trend in the forecast years. The use of analytical models based on big data machine learning is expected to increase product yields by enabling prediction and process parameters. Currently, disposables are being used more often by CMOs owing to the convenience of use and efficiency of SUTs in bioprocessing various products that require quick turnaround times.
Single-use Bioprocessing Market Segment Analysis:Based on Product, The simple and peripheral components segment led the single-use bioprocessing market, accounting for 49.0% of revenue in 2022. In terms of product availability and utilization, the highest penetration of filters, tubing, transfer systems, and connections has had a significant influence on revenue generation in this area. Advances in the single-use system, for example, have pushed bioprocess engineers to replace permanent pipe networks with single-use transfer lines. The availability of disposable bioprocess bags in a variety of sizes for a variety of applications allows market participants to capitalize on unexplored market opportunities and strengthen their market position. On the other hand, the biopharmaceutical industry's demand for disposable probes and sensors is constantly increasing. This demand is reported to be considered in the United States and Europe. Emerging and small firms are competing in this area by producing single-use sensors for measuring several properties during bioprocessing. Based on the Workflow, The upstream workflow segment led the single-use bioprocessing market, accounting for 57.5% of revenue in 2020. In contrast to downstream processing, single-use systems for upstream operations like as medium preparation, cell-culture seeding, aseptic sampling, and others are routinely available. With the rise of disposable bioprocess applications, industrial SUS providers are concentrating on providing sophisticated solutions to address productivity issues. SUT vendors are making rapid advances to increase the use of disposables in downstream processes. For example, the market launch of disposable unit operating systems for downstream processing such as pre-packed chromatography columns, filtration devices, pumps, and heat exchangers is increasing industry growth. Based on the End-use, The biopharmaceutical manufacturers sector led the market for single-use bioprocessing market, accounting for more than 62.0% of revenue in 2022. Owing to factors such as increasing adoption of single-use technologies and systems due to the benefits, reduced initial investment and R&D costs, low labor and material costs, and easily disposed of, offered over conventional bioprocessing methods, increasing demand for biologics, and rising company activities. The COVID-19 epidemic has disrupted the pharmaceutical supply chain. Many goods sold in nations such as the United States, Europe, and others have been impacted by limits on pharmaceutical production and export. Countries' health systems are increasingly investing in research and development to tackle the COVID-19 pandemic. To screen SARS-CoV-2 against a library of 50,000 chemicals, a single-use bioreactor must be used for flexibility and speed, while reducing overall operating costs to a low. In India, for example, the Prime Minister's Office (PMO)-established Vaccine Task Force (VTF) for targeted research on coronavirus vaccines and has permitted research institutes and laboratories to use patient samples for research and development (R&D). The government has developed clear standards for institutions to share biospecimens and data for such research. Furthermore, increased firm activity in producing Single-use Bioprocessing Market systems and consumables, as well as implementing various business strategies, are adding to the segment's growth. For example, Thermo Fischer Scientific will release 3,000 L and 5,000 L HyPerforma DynaDrive Single-use Bioreactors in March 2021. These bioreactors are designed to enable cell culture performance at several scales and to handle high-density and next-generation cell culture operations. In stirred tank reactors, DynaDrive S.U.B.s also provide improved turn-down, reducing the number of vessels required for seed-train scale-up. The DynaDrive S.U.B.s minimize total costs by decreasing seed-train and enabling large-scale, high-intensity operations. This is accomplished through lower capital investment, lower operational expenditures, and higher-output processes. In addition, Thermo Fisher Scientific will offer a single-use bioreactor (SUB) for cell culture production in December 2020. Additionally, these single-use bioprocessing market units have a 35% better carbon dioxide (CO2) balance than stainless steel reactors, which are often utilized in conventional bioprocessing and are widely employed by the manufacturer. In addition, the firms are establishing single-use bioprocessing units to enhance their protein, cell line, and process development capabilities. For example, in April 2022, Thermo Fisher Scientific will establish a 55,000-square-foot single-use technology (SUT) plant in Ogden to enhance the manufacturing of single-use bioprocess containers for producing vaccines and medicines. The factory adds the capacity to produce various procedures and materials required for the development of novel vaccines and medicines. The factory will produce bioprocess container (BPC) systems that may be customized for the delivery, processing, separation, storage, and transportation of liquids.
Regional Insights:With a revenue share of 38.5% in 2022, North America dominated the single-use bioprocessing market. Increasing R&D investment, the existence of large-scale manufacturing units, the growing popularity of disposables, growing healthcare expenditure, and the availability of well-established healthcare infrastructure are expected to drive growth during the forecast period. The United States is the world's most COVID-affected country. This country's goods supply chain was severely damaged. Initially, there is a drop in demand for single-use bioprocessing market goods, which has hampered market growth overall. However, as more people become aware of the necessity and benefits of single-use bioprocessing technologies, demand for them may progressively increase. Moreover, the government is spending heavily on the development of COVID-19 vaccines, treatments, and diagnostic tests, which is expected to fuel the demand for single-use bioreactors, hence driving the total Single-use Bioprocessing Market growth. For example, the Canadian government announced CAD 275.2 million (EUR 179.5 million) in March 2020 for COVID-19 research and development initiatives such as antivirals, diagnostics, vaccines, and clinical trials. In addition, Moderna Inc. won USD 483.5 million from the US government in April 2020 for the development of a COVID-19 vaccine. Disposables have been popular among contract manufacturing organizations (CMO), and this area is regarded as an important market for contract service providers. This element encourages local and global enterprises to continue investing in the region's contract development and manufacturing organizations and biomanufacturing facilities to deploy disposables. Moreover, increased business activity in constructing single-use bioprocessing facilities and releasing bioreactors and consumables are driving the single-use bioprocessing market growth throughout the forecast period. ILC Dover Lp, for example, released liquid single-use bioprocessing bags in May 2022 for handling and distributing sterile liquids for the biotherapeutics sector. This launch contributes to the company's efforts to broaden its product offerings in the single-use bioprocessing industry. In addition, Bionova will establish a USD 25.2 million single-use factory in Fremont, California, in November 2021. A 1,000 L Cytiva XDR upstream train is installed in the facility. In addition, by Q3'2022, the business will install a 2,000 L Cytiva system.
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Single-use Bioprocessing Market Report Coverage Details Base Year: 2022 Forecast Period: 2023-2029 Historical Data: 2018 to 2022 Market Size in 2022: US $ 11.97 Bn. Forecast Period 2023 to 2029 CAGR: 21% Market Size in 2029: US $ 45.49 Bn. Segments Covered: by Product 1. Simple & Peripheral Elements 1.2 Bags 1.3 Tubing, Filters, Connectors, & Transfer Systems 1.4 Sampling Systems 1.5 Probes & Sensors 1.1.2 pH Sensor 1.2.3Oxygen Sensors 1.2.4 Pressure Sensors 1.3.5 Temperature Sensors 1.4.6 Conductivity Sensors 1.5.7Flow Sensors 1.6.8Other sensors 1.7.9 Others 2.Apparatus & Plants 2.2Bioreactors, By Capacity 2.1.1Up to 1000L 2.2.2 Above 1000L to 2000L 3.3.3 Above 2000L 2.1 Filtration system 2.2 Mixing, Storage, & Filling Systems 2.3 Chromatography Systems 2.4 Pumps 2.5Others 4 Work Equipment 4.1Cell Culture System 4.2Syringes 4.3 Others by Workflow 1. Upstream 2.Fermentation 3.Downstream by End-use 1 Biopharmaceutical Manufacturer 1.2 CMOs & CROs 2.3In-house Manufacturer 2.Academic & Clinical Research Institutes
Single-use Bioprocessing Market, by RegionNorth America (United States, Canada and Mexico) Europe (UK, France, Germany, Italy, Spain, Sweden, Austria and Rest of Europe) Asia Pacific (China, South Korea, Japan, India, Australia, Indonesia, Malaysia, Vietnam, Taiwan, Bangladesh, Pakistan and Rest of APAC) Middle East and Africa (South Africa, GCC, Egypt, Nigeria and Rest of ME&A) South America (Brazil, Argentina Rest of South America)
Key Players are:1. Thermo Fisher Scientific (US) 2. Meissner Filtration Products, Inc.(US) 3. Danaher Corporation (US) 4. Corning(US) 5. Entegris(US) 6. Avantor(US) 7. PBS Biotech, Inc.(US) 8. Distek, Inc.(US) 9. ABEC, Inc.(US) 10.Able Corporation & Biott Corporation(US) 11.G&G Technologies(US) 12.Cellexus(UK) 13.Celltainer Biotech(Netherlands) 14.bbi-biotech GmbH( Germany) 15.Sartorius Stedim Biotech S.A.(Germany) 16.Eppendorf AG(Germany) 17.Merck KGaA(Germany) 18.Solida Biotech GmbH(Germany) 19.Pierre Guerin (France) 20.Kuhner AG(Switzerland) 21.Stobbe Pharma GmbH(Switzerland) 22.Getinge AB(Sweden) 23.OmniBRx Biotechnologies(India) 24.Satake Chemical Equipment Mfg., Ltd.(Japan) 25.CESCO Bioengineering Co. Ltd.(Taiwan) Frequently Asked Questions: 1] Which End-use segment led the single-use bioprocessing market? Ans. The biopharmaceutical manufacturers sector led the market for single-use bioprocessing market, accounting for more than 62.0% of revenue in 2022. 2] Which is the primary driver for the Single-use Bioprocessing Market? Ans. The Huge growth in the biopharmaceuticals sector is driving the market for Single-use Bioprocessing Market. 3] Who are the key companies/players in the single-use bioprocessing market? Ans. Some key participants in the single-use bioprocessing market for single-use bioprocessing include Thermo Fisher Scientific, Danaher Corporation, Merck KGaA, Getinge AB, Eppendorf AG , and Corning. 4] What is Bioprocessing Technology? Ans. Bioprocessing or biotechnology is the employment of a biocatalyst such as an enzyme, bacteria, plant cells, or animal cells in a bioreactor to produce medications, foods, flavors, fuels, and chemicals. 5] What is the modern application of Bioprocessing? Ans. The most important applications of bioprocess-engineering research and development in agriculture and food include the production of agricultural chemicals for the control of animal and plant diseases, growth-stimulating agents for increased yield, and biological insecticides and herbicides; increasing bioprocess efficiency; and increasing bioprocess yield.
1. Global Single-use Bioprocessing Market Size: Research Methodology 2. Global Single-use Bioprocessing Market Size: Executive Summary 2.1. Market Overview and Definitions 2.1.1. Introduction to Global Single-use Bioprocessing Market Size 2.2. Summary 2.2.1. Key Findings 2.2.2. Recommendations for Investors 2.2.3. Recommendations for Market Leaders 2.2.4. Recommendations for New Market Entry 3. Global Single-use Bioprocessing Market Size: Competitive Analysis 3.1. MMR Competition Matrix 3.1.1. Market Structure by region 3.1.2. Competitive Benchmarking of Key Players 3.2. Consolidation in the Market 3.2.1 M&A by region 3.3. Key Developments by Companies 3.4. Market Drivers 3.5. Market Restraints 3.6. Market Opportunities 3.7. Market Challenges 3.8. Market Dynamics 3.9. PORTERS Five Forces Analysis 3.10. PESTLE 3.11. Regulatory Landscape by region • North America • Europe • Asia Pacific • Middle East and Africa • South America 3.12. COVID-19 Impact 4. Global Single-use Bioprocessing Market Size Segmentation 4.1. Global Single-use Bioprocessing Market Size, by Product (2022-2029) • Simple & Peripheral Elements o Bags o Tubing, Filters, Connectors, & Transfer Systems o Sampling Systems o Probes & Sensors o pH Sensor o Oxygen Sensors o Pressure Sensors o Temperature Sensors o Conductivity Sensors o Flow Sensors o Other sensors o Others • Apparatus & Plants o Bioreactors, By Capacity o Up to 1000L o Above 1000L to 2000L o Above 2000L o Filtration system o Mixing, Storage, & Filling Systems o Chromatography Systems o Pumps o Others • Work Equipment o Cell Culture System o Syringes o Others 4.2. Global Single-use Bioprocessing Market Size, by Workflow (2022-2029) • Upstream • Fermentation • Downstream 4.3. Global Single-use Bioprocessing Market Size, by End Use (2022-2029) • Biopharmaceutical Manufacturer o CMOs & CROs o In-house Manufacturer • Academic & Clinical Research Institutes 5. North America Single-use Bioprocessing Market (2022-2029) 5.1. North America Single-use Bioprocessing Market Size, by Product (2022-2029) • Simple & Peripheral Elements o Bags o Tubing, Filters, Connectors, & Transfer Systems o Sampling Systems o Probes & Sensors o pH Sensor o Oxygen Sensors o Pressure Sensors o Temperature Sensors o Conductivity Sensors o Flow Sensors o Other sensors o Others • Apparatus & Plants • Bioreactors, By Capacity o Up to 1000L o Above 1000L to 2000L o Above 2000L o Filtration system o Mixing, Storage, & Filling Systems o Chromatography Systems o Pumps o Others • Work Equipment o Cell Culture System o Syringes o Others 5.2. North America Single-use Bioprocessing Market Size, by Workflow (2022-2029) • Upstream • Fermentation • Downstream 5.3. North America Single-use Bioprocessing Market Size, by End Use (2022-2029) • Biopharmaceutical Manufacturer o CMOs & CROs o In-house Manufacturer • Academic & Clinical Research Institutes 5.4. North America Semiconductor Memory Market, by Country (2022-2029) • United States • Canada • Mexico 6. European Single-use Bioprocessing Market (2022-2029) 6.1. European Single-use Bioprocessing Market, by Product (2022-2029) 6.2. European Single-use Bioprocessing Market, by Workflow (2022-2029) 6.3. European Single-use Bioprocessing Market, by End Use (2022-2029) 6.4. European Single-use Bioprocessing Market, by Country (2022-2029) • UK • France • Germany • Italy • Spain • Sweden • Austria • Rest Of Europe 7. Asia Pacific Single-use Bioprocessing Market (2022-2029) 7.1. Asia Pacific Single-use Bioprocessing Market, by Product (2022-2029) 7.2. Asia Pacific Single-use Bioprocessing Market, by Workflow (2022-2029) 7.3. Asia Pacific Single-use Bioprocessing Market, by End Use (2022-2029) 7.4. Asia Pacific Single-use Bioprocessing Market, by Country (2022-2029) • China • India • Japan • South Korea • Australia • ASEAN • Rest Of APAC 8. Middle East and Africa Single-use Bioprocessing Market (2022-2029) 8.1. Middle East and Africa Single-use Bioprocessing Market, by Product (2022-2029) 8.2. Middle East and Africa Single-use Bioprocessing Market, by Workflow (2022-2029) 8.3. Middle East and Africa Single-use Bioprocessing Market, by End Use (2022-2029) 8.4. Middle East and Africa Single-use Bioprocessing Market, by Country (2022-2029) • South Africa • GCC • Egypt • Nigeria • Rest Of ME&A 9. South America Single-use Bioprocessing Market (2022-2029) 9.1. South America Single-use Bioprocessing Market, by Product (2022-2029) 9.2. South America Single-use Bioprocessing Market, by Workflow (2022-2029) 9.3. South America Single-use Bioprocessing Market, by End Use (2022-2029) 9.4. South America Single-use Bioprocessing Market, by Country (2022-2029) • Brazil • Argentina • Rest Of South America 10. Company Profile: Key players 10.1. Sartorius Stedim Biotech S.A. 10.1.1. Company Overview 10.1.2. Financial Overview 10.1.3. Global Presence 10.1.4. Capacity Portfolio 10.1.5. Business Strategy 10.1.6. Recent Developments 10.2. Thermo Fisher Scientific 10.3. Danaher Corporation 10.4. Merck KGaA 10.5. Getinge AB 10.6. Eppendorf AG 10.7. Corning 10.8. Entegris 10.9. Avantor 10.10. CESCO Bioengineering Co. Ltd. 10.11. Cellexus 10.12. PBS Biotech, Inc. 10.13. Distek, Inc. 10.14. ABEC, Inc. 10.15. Able Corporation & Biott Corporation 10.16. G&G Technologies 10.17. Solida Biotech GmbH 10.18. Satake Chemical Equipment Mfg., Ltd. 10.19. Stobbe Pharma GmbH 10.20. Celltainer Biotech 10.21. Meissner Filtration Products, Inc. 10.22. bbi-biotech GmbH 10.23. Pierre Guerin 10.24. Kuhner AG 10.25. OmniBRx Biotechnologies